Evidence map›Paper›PMID 21602837›Full record

ArticleActa pharmacologica Sinica2011

Association of serum omentin-1 levels with coronary artery disease.

Xia Zhong, Hai-yang Zhang, Hui Tan, Yi Zhou, Fu-li Liu, Fu-qin Chen, De-ya Shang

Abstract read
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Article in Acta pharmacologica Sinica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  18. Omentin-A Novel Adipokine in Respiratory Diseases.International journal of molecular sciences · 2017
    Review
  19. Article
  20. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xia ZhongDepartment of Emergency, Provincial Hospital Affiliated to Shandong University, Ji-nan 250021, China.
Hai-yang Zhang
Hui Tan
Yi Zhou
Fu-li Liu
Fu-qin Chen
De-ya Shang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOmentin-1, a novel adipokine expressed in visceral adipose tissue, is negatively correlated with insulin resistance and obesity. Decreased omentin-1 expression has been found in many chronic inflammatory diseases. However, the role of omentin-1 in coronary artery disease (CAD) has not been elucidated. The aim of the present study was to determine whether serum concentration of omentin-1 was independently associated with CAD.

methodsOne hundred and fifty five patients with CAD were divided into two groups: acute coronary syndrome (ACS) and stable angina pectoris (SAP). A total of 52 healthy participants served as controls. Serum concentrations of omentin-1 and interleukin-6 (IL-6) were measured using ELISA. The association of omentin-1 with CAD and cardiovascular disease risk factors was evaluated.

resultsSerum omentin-1 levels were lower in patients with ACS or SAP compared with controls (ACS, 113.08±61.43 ng/mL; SAP, 155.41±66.89 ng/mL; control, 254.00±72.9 ng/mL; P<0.01). Patients with ACS also had lower serum concentrations of omentin-1 compared with patients with SAP (P<0.01). Serum concentration of omentin-1 was negatively correlated with body mass index (r=-0.17, P<0.05) and serum IL-6 concentration (r=-0.19, P<0.05). Furthermore, multiple logistic regression analysis showed that serum omentin-1 concentrations were independently correlated with CAD.

conclusionThe findings suggest that serum concentrations of omentin-1 are related to CAD.

Indexed as

AgedAngina PectorisCoronary Artery DiseaseCytokinesFemaleGPI-Linked ProteinsHumansInterleukin-6LectinsMaleMiddle AgedCytokinesGPI-Linked ProteinsInterleukin-6ITLN1 protein, humanLectins

Identifiers

PMID21602837
PMCPMC4003121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.