ReviewCurrent opinion in psychiatry2011
The role of latent internalizing and externalizing predispositions in accounting for the development of comorbidity among common mental disorders.
Review in Current opinion in psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Antisocial Disorders in Adolescence and Youth, According to Structural, Emotional, and Cognitive Transdiagnostic Variables: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- The global prevalence of common mental disorders: a systematic review and meta-analysis 1980-2013.International journal of epidemiology · 2014Pooled it
- Data-driven subtypes of major depressive disorder: a systematic review.BMC medicine · 2012Pooled it
- Child and adolescent psychiatry: challenges, solutions, opportunities, and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Combinations of mental disorders and their association with mortality in the UK Biobank.BMC psychiatry · 2026Article
- Does Parental Mental Health Moderate the Association between Parenting Stress and Child Externalizing Behaviors Among Autistic Children?Child psychiatry and human development · 2026Article
- Article
- The structure of mood and anxiety disorder symptoms in the perinatal period.Journal of affective disorders · 2023Article
- The validity of transdiagnostic factors in predicting homotypic and heterotypic continuity of psychopathology symptoms over time.Frontiers in psychiatry · 2023Article
- Internalizing-Externalizing Comorbidity and Impaired Functioning in Children.Children (Basel, Switzerland) · 2022Article
- Subtyping of Internalizing and Externalizing Behaviors in Japanese Community-Based Children: A Latent Class Analysis and Association with Family Activities.Children (Basel, Switzerland) · 2022Article
- The structure of dimensions of psychopathology in normative and clinical samples: Applying causal discovery to MMPI-2-RF scales to investigate clustering of psychopathology spectra andFrontiers in psychiatry · 2022Article
- Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population-based cohort study.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020Article
- A choose your own adventure story: Conceptualizing depression in children and adolescents from traditional DSM and alternative latent dimensional approaches.Behaviour research and therapy · 2019Review
- A Hierarchical Taxonomy of Psychopathology Can Transform Mental Health Research.Perspectives on psychological science : a journal of the Association for Psychological Science · 2019Review
- Reduced Resting State Neural Activity in the Right Orbital Part of Middle Frontal Gyrus in Anxious Depression.Frontiers in psychiatry · 2019Article
- Internet- and mobile-based aftercare and relapse prevention in mental disorders: A systematic review and recommendations for future research.Internet interventions · 2018Review
- The cross-national structure of mental disorders: results from the World Mental Health Surveys.Psychological medicine · 2018Article
- Implications of the Hierarchical Structure of Psychopathology for Psychiatric Neuroimaging.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- A hierarchical causal taxonomy of psychopathology across the life span.Psychological bulletin · 2017Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purpose of reviewAlthough numerous studies have examined the latent structure of internalizing and externalizing mental disorders, the effects of this structure in predicting the development of comorbidity have remained unexamined until recently. RECENT
findingsA novel approach to study the effects of latent internalizing and externalizing predispositions to the development of comorbidity was used to analyze data from 14 countries in the WHO World Mental Health Survey Initiative. Pervasive significant positive associations were found between temporally primary and secondary internalizing and externalizing disorders in survival analyses, with time-lagged associations consistently stronger within domains than between domains. The vast majority of these associations were explained by latent internalizing and externalizing variables. Specific phobia and obsessive compulsive disorder were the most important internalizing components and hyperactivity disorder and oppositional-defiant disorder the most important externalizing components. Several intriguing residual time-lagged associations remained significant, though, even after controlling latent predispositions. SUMMARY: The latent variable model suggests that common causal pathways account for most comorbidity among internalizing-externalizing disorders. These pathways should be the focus of future research on the development of comorbidity, although isolation of consistent residual time-lagged associations between certain pairs of primary-secondary disorders is also important in pointing the way to subsequent focused study.
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