ArticleThe Journal of clinical endocrinology and metabolism2011
Approach to the girl with early onset of pubic hair.
Article in The Journal of clinical endocrinology and metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 73 citations in OpenAlex.
- Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL-Related Disorders: A Cross-Sectional Caregiver Survey Analysis.American journal of medical genetics. Part A · 2026Article
- Body composition in prepubertal children with idiopathic premature adrenarche: implications for cardiometabolic health.Pediatric research · 2025Observational
- Mapping the Fat: How Childhood Obesity and Body Composition Shape Obstructive Sleep Apnoea.Children (Basel, Switzerland) · 2025Review
- Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023Article
- Precocious Puberty.Indian journal of pediatrics · 2023Review
- Case Report: Adrenocortical carcinoma in children-symptoms, diagnosis, and treatment.Frontiers in endocrinology · 2023Review
- Differentiating Polycystic Ovary Syndrome from Adrenal Disorders.Diagnostics (Basel, Switzerland) · 2022Review
- Article
- Delayed pubarche.Italian journal of pediatrics · 2021Review
- The Unique Role of 11-Oxygenated C19 Steroids in Both Premature Adrenarche and Premature Pubarche.Hormone research in paediatrics · 2020Article
- Management of the Female With Non-classical Congenital Adrenal Hyperplasia (NCCAH): A Patient-Oriented Approach.Frontiers in endocrinology · 2019Review
- Metabolic Perspectives for Non-classical Congenital Adrenal Hyperplasia With Relation to the Classical Form of the Disease.Frontiers in endocrinology · 2019Review
- Body mass index at the presentation of premature adrenarche is associated with components of metabolic syndrome at puberty.European journal of pediatrics · 2018Article
- The tempo of human childhood: a maternal foot on the accelerator, a paternal foot on the brake.Evolutionary anthropology · 2018Review
- Polycystic Ovary Syndrome (PCOS), Diagnostic Criteria, and AMHAsian Pacific journal of cancer prevention : APJCP · 2017Article
- Value of ultrasonography in the diagnosis of polycystic ovary syndrome - literature review.Journal of ultrasonography · 2015Review
- Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome.Endocrine reviews · 2015 · on this mapReview
- Premature pubarche in children with Pompe disease.The Journal of pediatrics · 2015Article
- Higher body fat and lower fat-free mass in girls with premature adrenarche.Journal of clinical research in pediatric endocrinology · 2015Article
- The Relationship of Metabolic Syndrome and Body Composition in Children with Premature Adrenarche: Is It Age Related?Hormone research in paediatrics · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Premature pubarche, or the development of pubic hair before the age of 8 in girls or 9 in boys, is most commonly caused by premature adrenarche. Adrenarche is the maturation of the adrenal zona reticularis in both boys and girls, resulting in the development of pubic hair, axillary hair, and adult apocrine body odor. Although originally thought to be a benign variant of normal development, premature adrenarche has been associated with insulin resistance and the later development of metabolic syndrome and polycystic ovary syndrome. Although further studies are needed to confirm these relationships, the case presented herein argues for periodic assessment of children at risk. Indeed, recognition of these associations may allow for early preventive measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.