ArticleApplied and environmental microbiology2011
Dehydrogenase GRD1 represents a novel component of the cellulase regulon in Trichoderma reesei (Hypocrea jecorina).
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Determining the Effects of Light on the Fruit Peel Quality of Photosensitive and Nonphotosensitive Eggplant.Plants (Basel, Switzerland) · 2022Article
- Review
- The Kinase USK1 Regulates Cellulase Gene Expression and Secondary Metabolite Biosynthesis inFrontiers in microbiology · 2020Article
- Protein phosphatases regulate growth, development, cellulases and secondary metabolism in Trichoderma reesei.Scientific reports · 2019Article
- Enhancement of cellulase production in Trichoderma reesei RUT-C30 by comparative genomic screening.Microbial cell factories · 2019Article
- Regulation of plant cell wall degradation by light inFungal biology and biotechnology · 2018Review
- Improving cellulase production in submerged fermentation by the expression of a Vitreoscilla hemoglobin in Trichoderma reesei.AMB Express · 2017Article
- Abundance of Secreted Proteins ofFrontiers in microbiology · 2017Article
- Experimental Evolution of Trichoderma citrinoviride for Faster Deconstruction of Cellulose.PloS one · 2016Article
- The effects of extracellular pH and of the transcriptional regulator PACI on the transcriptome of Trichoderma reesei.Microbial cell factories · 2015Article
- Targets of light signalling in Trichoderma reesei.BMC genomics · 2013Article
- Roles of protein kinase A and adenylate cyclase in light-modulated cellulase regulation in Trichoderma reesei.Applied and environmental microbiology · 2012Article
- A versatile toolkit for high throughput functional genomics with Trichoderma reesei.Biotechnology for biofuels · 2012Article
- The phosducin-like protein PhLP1 impacts regulation of glycoside hydrolases and light response in Trichoderma reesei.BMC genomics · 2011Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Trichoderma reesei (Hypocrea jecorina) is nowadays the most important industrial producer of cellulase and hemicellulase enzymes, which are used for pretreatment of cellulosic biomass for biofuel production. In this study, we introduce a novel component, GRD1 (glucose-ribitol dehydrogenase 1), which shows enzymatic activity on cellobiose and positively influences cellulase gene transcription, expression, and extracellular endo-1,4-β-D-glucanase activity. grd1 is differentially transcribed upon growth on cellulose and the induction of cellulase gene expression by sophorose. The transcription of grd1 is coregulated with that of cel7a (cbh1) under inducing conditions. GRD1 is further involved in carbon source utilization on several carbon sources, such as those involved in lactose and D-galactose catabolism, in several cases in a light-dependent manner. We conclude that GRD1 represents a novel enhancer of cellulase gene expression, which by coregulation with the major cellulase may act via optimization of inducing mechanisms.
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