Evidence map›Paper›PMID 21601262›Full record

ArticleTheriogenology2011

Influence of lameness on follicular growth, ovulation, reproductive hormone concentrations and estrus behavior in dairy cows.

M J Morris, K Kaneko, S L Walker, D N Jones, J E Routly, R F Smith, H Dobson

Open access · hybridAbstract read
In one paragraph

Article in Theriogenology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 80 citations in OpenAlex.

  1. The Puerperium in the Modern Dairy Cow: A Review.Reproduction in domestic animals = Zuchthygiene · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Finding biomarkers of experience in animals.Journal of animal science and biotechnology · 2024
    Review
  6. Review
  7. Article
  8. Cattle Body Detection Based on YOLOv5-EMA for Precision Livestock Farming.Animals : an open access journal from MDPI · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Distribution of lameness lesions in beef cattle: A retrospective analysis of 745 cases.The Canadian veterinary journal = La revue veterinaire canadienne · 2016
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

M J MorrisSchool of Veterinary Science, University of Liverpool, Neston, Wirral UK.
K Kaneko
S L Walker
D N Jones
J E Routly
R F Smith
H Dobson
University of Liverpool · GBChester Zoo · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The objective of this study was to examine the effect of a chronic stressor, lameness, on reproductive parameters. Seventy cows 30-80 days post-partum were scored for lameness and follicular phases synchronized with GnRH followed seven days later by prostaglandin (PG). Fifteen Lame animals did not respond to GnRH ovarian stimulation. Milk progesterone for 5 days prior to PG was lower in the remaining Lame cows than Healthy herdmates. Fewer Lame cows ovulated (26/37 versus 17/18; P = 0.04) and the interval from PG to ovulation was shorter in Lame cows. In Subset 1 (20 animals), the LH pulse frequency was similar in ovulating animals (Lame and Healthy) but lower in Lame non-ovulators. An LH surge always preceded ovulation but lameness did not affect the interval from PG to LH surge onset or LH surge concentrations. Before the LH surge, estradiol was lower in non-ovulating cows compared to those that ovulated and estradiol concentrations were positively correlated with LH pulse frequency. In Subset 2 (45 cows), Lame ovulating cows had a less intense estrus than Healthy cows, although Lame cows began estrus and stood-to-be-mounted earlier than Healthy cows. In conclusion, we have identified several parameters to explain poor fertility in some chronically stressed animals. From 30 to 80 days post-partum, there was a graded effect that ranged from 29% Lame cows with absence of ovarian activity, whereas another 21% Lame cows failed to express estrus or ovulate a low estrogenic follicle; in 50% cows, many reproductive parameters were unaffected by lameness.

Indexed as

AnimalsCattleCattle DiseasesChi-Square DistributionEstradiolEstrous CycleFemaleLameness, AnimalLuteinizing HormoneMilkOvarian FollicleOvulation InductionProgesteroneUltrasonographyEstradiolLuteinizing HormoneProgesterone

Identifiers

PMID21601262
PMCPMC3156299
OpenAlexW1968904837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.