ArticleAmerican journal of human genetics2011
A revised root for the human Y chromosomal phylogenetic tree: the origin of patrilineal diversity in Africa.
Article in American journal of human genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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54 citing papers in PubMed.
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- The ancestry and geographical origins of St Helena's liberated Africans.American journal of human genetics · 2023Article
- Contrasting maternal and paternal genetic histories among five ethnic groups from Khyber Pakhtunkhwa, Pakistan.Scientific reports · 2022Article
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- New insights into the evolution of human Y chromosome palindromes through mutation and gene conversion.Human molecular genetics · 2021Article
- African genetic diversity and adaptation inform a precision medicine agenda.Nature reviews. Genetics · 2021Review
- Y-Chromosome Variation in Southern African Khoe-San Populations Based on Whole-Genome Sequences.Genome biology and evolution · 2020Article
- GADMA: Genetic algorithm for inferring demographic history of multiple populations from allele frequency spectrum data.GigaScience · 2020Article
- A dispersal of Homo sapiens from southern to eastern Africa immediately preceded the out-of-Africa migration.Scientific reports · 2019Article
- Paternal origin of Paleo-Indians in Siberia: insights from Y-chromosome sequences.European journal of human genetics : EJHG · 2018Article
- Carriers of mitochondrial DNA macrohaplogroup L3 basal lineages migrated back to Africa from Asia around 70,000 years ago.BMC evolutionary biology · 2018Article
- Genetic Diversity on the Sex Chromosomes.Genome biology and evolution · 2018Review
- Using Y-Chromosomal Haplogroups in Genetic Association Studies and Suggested Implications.Genes · 2018Article
- Human ancestry correlates with language and reveals that race is not an objective genomic classifier.Scientific reports · 2017Article
- The study of human Y chromosome variation through ancient DNA.Human genetics · 2017Review
- Evidence of extensive non-allelic gene conversion among LTR elements in the human genome.Scientific reports · 2016Article
- Ancient Human Migration after Out-of-Africa.Scientific reports · 2016Article
- Refining the Y chromosome phylogeny with southern African sequences.Human genetics · 2016Article
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6 authors.
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Abstract
To shed light on the structure of the basal backbone of the human Y chromosome phylogeny, we sequenced about 200 kb of the male-specific region of the human Y chromosome (MSY) from each of seven Y chromosomes belonging to clades A1, A2, A3, and BT. We detected 146 biallelic variant sites through this analysis. We used these variants to construct a patrilineal tree, without taking into account any previously reported information regarding the phylogenetic relationships among the seven Y chromosomes here analyzed. There are several key changes at the basal nodes as compared with the most recent reference Y chromosome tree. A different position of the root was determined, with important implications for the origin of human Y chromosome diversity. An estimate of 142 KY was obtained for the coalescence time of the revised MSY tree, which is earlier than that obtained in previous studies and easier to reconcile with plausible scenarios of modern human origin. The number of deep branchings leading to African-specific clades has doubled, further strengthening the MSY-based evidence for a modern human origin in the African continent. An analysis of 2204 African DNA samples showed that the deepest clades of the revised MSY phylogeny are currently found in central and northwest Africa, opening new perspectives on early human presence in the continent.
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