Evidence map›Paper›PMID 21597931›Full record

ReviewCurrent atherosclerosis reports2011

Current management of symptomatic intracranial stenosis.

Robert A Taylor, John B Weigele, Scott E Kasner

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Robert A TaylorDepartment of Neurology, University of Minnesota, Minneapolis, USA. rataylor@umn.edu
John B Weigele
Scott E Kasner
University of Minnesota · USUniversity of Pennsylvania · USUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial arterial stenosis (IAS) is the cause of about 10% of all ischemic strokes in the United States, but may account for about 40% of strokes in some populations. After a stroke or transient ischemic attack due to IAS, patients face a 12% annual risk of recurrent stroke on medical therapy, with most strokes occurring in the first year. Warfarin is no better than aspirin in preventing recurrent strokes but poses a higher risk of serious bleeding and death. Groups with the highest risk of recurrent stroke are those with high-grade (≥ 70%) stenosis, those with recent symptom onset, those with symptoms precipitated by hemodynamic maneuvers, and women. Endovascular treatment of IAS is a rapidly evolving therapeutic option. Antiplatelet agents are currently recommended as the primary treatment for symptomatic IAS, with endovascular therapy reserved for appropriate high-risk cases refractory to medical therapy.

Indexed as

AngioplastyAnticoagulantsAtorvastatinBrainBrain IschemiaCilostazolConstriction, PathologicEndovascular ProceduresFibrinolytic AgentsHeptanoic AcidsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIntracranial ArteriosclerosisPhosphodiesterase 3 InhibitorsPlatelet Aggregation InhibitorsPyrrolesAnticoagulantsAtorvastatinCilostazolFibrinolytic AgentsHeptanoic AcidsHydroxymethylglutaryl-CoA Reductase InhibitorsPhosphodiesterase 3 InhibitorsPlatelet Aggregation InhibitorsPyrrolesTetrazoles

Identifiers

PMID21597931
OpenAlexW2141145382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.