Evidence map›Paper›PMID 21597146›Full record

ArticleNanotechnology2011

Fluorescent magnetic hybrid nanoprobe for multimodal bioimaging.

Dmitry Koktysh, Vanessa Bright, Wellington Pham

Abstract read
In one paragraph

Article in Nanotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dmitry KoktyshDepartment of Chemistry, Vanderbilt University, Station B 351822, Nashville, TN 37235, USA.
Vanessa Bright
Wellington Pham
Vanderbilt University · US

Funding

Develop hybrid optical-magneto nanoprobes for tracking dendritic cellsR03EB009524 · NIBIB · VANDERBILT UNIVERSITY · PI KOKTYSH, DMITRY S, PHAM, WELLINGTON · 2009 to 2010
$155k
NIBIB NIH HHS R03 EB009524NIBIB NIH HHS R03EB009-524
6 · The paper itself

Abstract

A fluorescent magnetic hybrid imaging nanoprobe (HINP) was fabricated by the conjugation of superparamagnetic Fe3O4 nanoparticles and visible light emitting (∼600 nm) fluorescent CdTe/CdS quantum dots (QDs). The assembly strategy used the covalent linking of the oxidized dextran shell of magnetic particles to the glutathione ligands of QDs. The synthesized HINP formed stable water-soluble colloidal dispersions. The structure and properties of the particles were characterized by transmission electron and atomic force microscopy, energy dispersive x-ray analysis and inductively coupled plasma optical emission spectroscopy, dynamic light scattering analysis, optical absorption and photoluminescence spectroscopy, and fluorescent imaging. The luminescence imaging region of the nanoprobe was extended to the near-infrared (NIR) (∼800 nm) by conjugation of the superparamagnetic nanoparticles with synthesized CdHgTe/CdS QDs. Cadmium, mercury based QDs in HINP can be easily replaced by novel water-soluble glutathione stabilized AgInS2/ZnS QDs to present a new class of cadmium-free multimodal imaging agents. The observed NIR photoluminescence of fluorescent magnetic nanocomposites supports their use for bioimaging. The developed HINP provides dual-imaging channels for simultaneous optical and magnetic resonance imaging.

Indexed as

MagneticsAbsorptionCadmium CompoundsFerric CompoundsFluorescenceHydrodynamicsLigandsMagnetic Resonance ImagingMolecular ProbesNanoparticlesParticle SizePhantoms, ImagingQuantum DotsSpectrometry, FluorescenceSulfidesTelluriumCadmium Compoundscadmium sulfidecadmium tellurideFerric Compoundsferric oxideLigandsMolecular ProbesSulfidesTellurium

Identifiers

PMID21597146
PMCPMC3133788
OpenAlexW2033723381

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.