Evidence map›Paper›PMID 21594742›Full record

ArticleIn vitro cellular & developmental biology. Animal2011

Generation and identification of rat fetal cerebral radial glia-like cells in vitro.

Haoming Li, Guohua Jin, Jianbing Qin, Meiling Tian, Xuefeng Tan, Xinhua Zhang, Weiwei Yang, Jinhong Shi, Linqing Zou

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Haoming LiDepartment of Anatomy and Neurobiology, the Jiangsu Key Laboratory of Neuroregeneration, Nantong University, No. 19 Qixiu Road, Nantong, China.
Guohua Jin
Jianbing Qin
Meiling Tian
Xuefeng Tan
Xinhua Zhang
Weiwei Yang
Jinhong Shi
Linqing Zou
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of radial glia cells (RGCs) as neural progenitors and as guides for migrating neurons is well established, mouse or human-derived radial glia (RG)-like cells in vitro showed some astroglia and stem/progenitor properties like RGCs in vivo, but different species-derived RG-like cells present some different properties. Here we acquired rat-derived RG-like cells on adherent conditions in vitro and then identified their astroglia and stem/progenitor properties. Similarly to the RGCs, the RG-like cells could be double-labeled by brain lipid-binding protein, glial fibrillary acidic protein, vimentin with nestin and expressed some astroglia and stem/progenitor genes; these cells also presented tripotent differentiation potentialities, albeit the ability of gliogenesis far exceeded the neurogenesis in vitro. Taken together, we acquired and identified some properties of rat-derived RG-like cells from fetal cerebral cortices in vitro.

Indexed as

AnimalsBiomarkersCell DifferentiationCells, CulturedCerebral CortexFemaleFetusHumansIntermediate Filament ProteinsMiceNerve Tissue ProteinsNestinNeurogliaPregnancyRatsRats, Sprague-DawleyBiomarkersIntermediate Filament ProteinsNerve Tissue ProteinsNES protein, humanNes protein, mouseNes protein, ratNestin

Identifiers

PMID21594742
OpenAlexW1987781672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.