ArticleWorld journal of surgery2011
Barrett's esophagus after resection of the gastroesophageal junction: effects of concomitant fundoplication.
Article in World journal of surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Columnar epithelium morphology after esophagectomy: clinical insight into the development of Barrett's esophagus.Esophagus : official journal of the Japan Esophageal Society · 2020Article
- Oesophagus: A new candidate for the progenitor cell of Barrett metaplasia.Nature reviews. Gastroenterology & hepatology · 2018Article
- Laparoscopic gastric wedge resection and prophylactic antireflux surgery for a submucosal tumor of gastroesophageal junction.Journal of gastric cancer · 2011Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBarrett's metaplasia has been known to occur after esophagectomy or gastrectomy in which the gastroesophageal junction with its associated lower esophageal sphincter has been resected. It is thought to be secondary to the refluxogenic nature of the operation. The present study was based on the hypothesis that patients who undergo a fundoplication with the resection would have a lower incidence of the development of postoperative Barrett's metaplasia.
methodsAll patients who underwent any type of esophagectomy or proximal gastrectomy in which the gastroesophageal junction was resected and an esophagogastrostomy performed were eligible for the study. Data gathered included age, gender, preoperative diagnosis, operation, postoperative pathology, occurrence and timing of postoperative upper endoscopy, and presence of Barrett's metaplasia on postoperative endoscopy. Statistical analysis was done with Fisher's exact test.
resultsOf the 179 patients who underwent resection, 151 had follow-up endoscopy documenting the presence or absence of Barrett's esophagus. Follow-up ranged from 6 months to 10 years. Of the 53 patients without fundoplications, 8 (18%) had Barrett's esophagus on follow-up upper endoscopy. Of the 98 patients with fundoplications, 5 (6%) had Barrett's esophagus (P = 0.04).
conclusionsThe present study suggests that concomitant fundoplication with resection of the gastroesophageal junction may have some protective effect against the development of Barrett's esophagus. A randomized trial will be required to prove this assertion. Also, it is still unclear as to the consequences of the development of post-resection Barrett's esophagus.
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