Evidence map›Paper›PMID 21593783›Full record

ArticleJournal of human hypertension2012

Patterns of sodium and potassium excretion and blood pressure in the African Diaspora.

B O Tayo, A Luke, C A McKenzie, H Kramer, G Cao, R Durazo-Arvizu, T Forrester, A A Adeyemo, R S Cooper

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of human hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. 24-hour sodium and potassium excretion in the Americas: a systematic review and meta-analysis.Revista panamericana de salud publica = Pan American journal of public health · 2022
    Review
  4. Article
  5. Association between urinary potassium excretion and blood pressure: A systematic review and meta-analysis of observational studies.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020
    Review
  6. Diet and Chronic Kidney Disease.Advances in nutrition (Bethesda, Md.) · 2019
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Seasonal variation in natural abundance of 2H and 18O in urine samples from rural Nigeria.Journal of applied physiology (Bethesda, Md. : 1985) · 2015
    Article
  13. Impact of westernization on fibroblast growth factor 23 levels among individuals of African ancestry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2015
    Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

B O TayoDepartment of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 60153, USA.
A Luke
C A McKenzie
H Kramer
G Cao
R Durazo-Arvizu
T Forrester
A A Adeyemo
R S Cooper
Loyola University Chicago · USUniversity of the West Indies · JMUniversity of Ibadan · NG

Funding

GENETICS OF HYPERTENSION IN BLACKSR01HL053353 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI COOPER, RICHARD STANLEY · 1995 to 2013
$8.3M
HYPERTENSION IN POPULATIONS OF WEST AFRICAN ORIGINR37HL045508 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI COOPER, RICHARD STANLEY · 1998 to 2008
$3.3M
NHLBI NIH HHS R01 HL053353NHLBI NIH HHS R01HL 053353NHLBI NIH HHS R37 HL045508NHLBI NIH HHS R37HL045508
6 · The paper itself

Abstract

Habitual levels of dietary sodium and potassium are correlated with age-related increases in blood pressure (BP) and likely have a role in this phenomenon. Although extensive published evidence exists from randomized trials, relatively few large-scale community surveys with multiple 24-h urine collections have been reported. We obtained three 24-h samples from 2704 individuals from Nigeria, Jamaica and the United States to evaluate patterns of intake and within-person relationships with BP. The average (±s.d.) age and weight of the participants across all the three sites were 39.9±8.6 years and 76.1±21.2 kg, respectively, and 55% of the total participants were females. Sodium excretion increased across the East-West gradient (for example, 123.9±54.6, 134.1±48.8, 176.6±71.0 (±s.d.) mmol, Nigeria, Jamaica and US, respectively), whereas potassium was essentially unchanged (for example, 46.3±22.9, 40.7±16.1, 44.7±16.4 (±s.d.) mmol, respectively). In multivariate analyses both sodium (positively) and potassium (negatively) were strongly correlated with BP (P<0.001); quantitatively the association was stronger, and more consistent in each site individually, for potassium. The within-population day-to-day variation was also greater for sodium than for potassium. Among each population group, a significant correlation was observed between sodium and urine volume, supporting the prior finding of sodium as a determinant of fluid intake in free-living individuals. These data confirm the consistency with the possible role of dietary electrolytes as hypertension risk factors, reinforcing the relevance of potassium in these populations.

Indexed as

Blood PressureNatriuresisAdultBlack or African AmericanBlack PeopleCultural CharacteristicsDrinkingFemaleHumansHypertensionJamaicaLife StyleLinear ModelsMaleMiddle AgedMultivariate AnalysisPotassium, DietarySodium Chloride, Dietary

Identifiers

PMID21593783
PMCPMC3158967
OpenAlexW2160172973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.