ArticleJournal of human hypertension2012
Health-related quality of life is worse in individuals with hypertension under drug treatment: results of population-based study.
Article in Journal of human hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trends in prevalence of hypertension in Brazil: a systematic review with meta-analysis.PloS one · 2012Pooled it
- Trial
- Impact on Health-Related Quality of Life after Different Aerobic Exercise Programs in Physically Inactive Adults with Overweight/Obesity and Primary Hypertension: Data from the EXERDIET-HTA Study.International journal of environmental research and public health · 2020Trial
- Health-related quality of life in blood pressure control and blood lipid-lowering therapies: results from the CHIEF randomized controlled trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Trial
- Dietary Approach to Stop Hypertension with Sodium Reduction for Chinese Canadians (DASHNa-CC): A Pilot Randomized Controlled Trial.The journal of nutrition, health & aging · 2017Trial
- Lifestyle Habits and Comorbidities as Determinants of Quality of Life in Coronary Artery Disease: A Single-Center Prospective Study.Journal of clinical medicine · 2026Article
- Determinants of Quality of Life Among Hemodialysis Patients: Roles of Associated Comorbidities, Smoking, Climate Change, and Residence.Journal of nutrition and metabolism · 2026Article
- Acceptance of Illness and Health-Related Quality of Life in Patients After Myocardial Infarction-Narrative Review.Journal of clinical medicine · 2025Review
- Experience of the Burden of Using Multiple Medicines and the Associated Impact on Health-Related Quality of Life.Journal of patient experience · 2025Article
- Observational
- A prospective longitudinal approach to examine the association between social position in childhood, adolescence, and adulthood with the control of hypertension during adulthood.Frontiers in public health · 2024Article
- Psychosocial factors influencing quality of life in patients with primary brain tumors in Pakistan: an analytical cross-sectional study.BMC research notes · 2023Article
- The association between sleep architecture, quality of life, and hypertension in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Article
- Cross-cultural adaptation of the Spanish MINICHAL instrument into English for use in the United Kingdom.Health and quality of life outcomes · 2022Article
- The Impact of Risk Factor Control on Health-Related Quality of Life in Individuals with High Cardiovascular Disease Risk: A Cross-sectional Study Based on EQ-5D Utility Scores in Inner Mongolia, China.Journal of epidemiology and global health · 2022Article
- Article
- Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study.Health and quality of life outcomes · 2021Article
- Depression: another cortisol-related comorbidity in patients with adrenal incidentalomas and (possible) autonomous cortisol secretion.Journal of endocrinological investigation · 2021Observational
- Significance of psychosocial factors in cardiology: update 2018 : Position paper of the German Cardiac Society.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Review
- Hypertension and Health-Related Quality of Life (HRQoL): Evidence from the US Hispanic Population.Clinical drug investigation · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with hypertension usually report lower health-related quality of life (HRQoL), but it is unclear whether this is secondary to high blood pressure (BP) per se, drug treatment or awareness of disease. In a cross-sectional study using a multistage population-based sample, participants were interviewed and examined at home. Hypertension was defined by BP ≥140/90 mm Hg or use of BP-lowering drugs. HRQoL was assessed through the Short-Form Health Survey (SF-12) and presented as the physical component summary (PCS), mental component summary (MCS) and the SF-12 eight-domain scale. In total, 1858 individuals were evaluated, being 60.1% women, aged 52.5 ± 4.1 years old, and 39.9% men, aged 47.2 ± 9.1 years old. Prevalence of hypertension was 34.2% (95% CI 31.5-36.9). The PCS scores for hypertensive and normotensive participants were 49.4 (CI 48.6-50.2) and 51.06 (CI 50.4-51.7) (P=0.01), respectively, and the MCS scores were 49.1 (CI 47.9-50.3) and 50.5 (CI 49.6-51.2) (P=0.06), respectively. Participants with hypertension and not using BP drugs had higher HRQoL scores (PCS 49.6; MCS 51.9) than those using BP drugs either with uncontrolled (PCS 45.3; MCS 49.4) or controlled BP (PCS 46.2; MCS 47.7; P<0.05). We concluded that individuals with hypertension have worse quality of life, particularly when their BP is controlled by drugs. This perception may lead to lower rates of adherence to treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.