Evidence map›Paper›PMID 21593492›Full record

Trial reportThe American journal of clinical nutrition2011

Long-term habituation to food in obese and nonobese women.

Leonard H Epstein, Katelyn A Carr, Meghan D Cavanaugh, Rocco A Paluch, Mark E Bouton

3 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01208870 nacompletednot on this map

Translating Habituation Research to Interventions for Pediatric Obesity

TypeinterventionalSponsorState University of New York at BuffaloRan2009 to 2014Enrolled94ConditionsPediatric Obesity, HabituationArmsVariety Group, Nutrition Education Control
NCT02481362 nacompletednot on this mapstarted 2015, after this paper: background citation

Food Choices in Healthy Weight Women

TypeinterventionalSponsorThe University of Tennessee, KnoxvilleRan2015 to 2016Enrolled28ConditionsAddictive Behavior, Food Preferences, Food Habits, HealthyArmsCAKE, APRICOTS
NCT04027426 nacompletednot on this mapstarted 2019, after this paper: background citation

Families Becoming Healthy Together

TypeinterventionalSponsorThe University of Tennessee, KnoxvilleRan2019 to 2025Enrolled83ConditionsObesity, Childhood ObesityArmsFBT, FBT+Variety
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  16. Mental imagery and food consumption.Frontiers in psychiatry · 2015
    Review
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  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Leonard H EpsteinSchool of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14214-3000, USA. lhenet@buffalo.edu
Katelyn A Carr
Meghan D Cavanaugh
Rocco A Paluch
Mark E Bouton

Funding

Translating Habituation Research to Interventions for Pediatric ObesityU01DK088380 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EPSTEIN, LEONARD H · 2009 to 2013
$2.9M
NIDDK NIH HHS 1U01 DK088380
6 · The paper itself

Abstract

backgroundHabituation is a form of learning in which repeated exposure to a stimulus leads to a decrease in responding. Eating involves repeated presentation of the same food stimulus in a meal, and habituation is reliably observed within a meal such that faster rates of habituation are associated with less energy intake. It is possible that repeated presentation of the same food over days will lead to long-term habituation, such that subjects habituate to foods repeated over meals. However, no research on long-term habituation to food in humans has been conducted.

objectiveThe current study was designed to assess long-term habituation in 16 obese and 16 nonobese premenopausal women.

designObese and nonobese women (aged 20-50 y) were randomly assigned to receive a macaroni and cheese meal presented 5 times, either daily for 1 wk or once per week for 5 wk.

resultsIn both obese and nonobese women, daily presentation of food resulted in faster habituation and less energy intake than did once-weekly presentation of food.

conclusionsLong-term habituation was observed when the same food was presented at daily meals but not when presented once weekly for 5 wk. These results provide the first evidence of long-term habituation to food in women and show that memory of food over daily meals can increase the rate of habituation and reduce energy intake. This trial was registered at clinicaltrials.gov as NCT01208870.

Indexed as

Habituation, PsychophysiologicAdultBehavior, AddictiveEnergy IntakeFeeding BehaviorFemaleHumansHyperphagiaMiddle AgedObesity

Identifiers

PMID21593492
PMCPMC3142716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.