Trial reportBMJ (Clinical research ed.)2011
Lateral wedge insoles for medial knee osteoarthritis: 12 month randomised controlled trial.
Trial report in BMJ (Clinical research ed.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00415259 (Effects of Shoes Insoles on Symptoms and Disease Progression in Knee Osteoarthritis), which is not on this map. Cited by 66 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Shoes Insoles on Symptoms and Disease Progression in Knee Osteoarthritis
Who cites it
66 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Effects of orthopedic insoles on patients with knee osteoarthritis: A meta-analysis and systematic review.Journal of rehabilitation medicine · 2021Pooled it
- Ineffectiveness of lateral-wedge insoles on the improvement of pain and function for medial knee osteoarthritis: a meta-analysis of controlled randomized trials.Archives of orthopaedic and trauma surgery · 2018Pooled it
- A systematic review of randomised controlled trials assessing effectiveness of prosthetic and orthotic interventions.PloS one · 2018Pooled it
- Pooled it
- Braces and orthoses for treating osteoarthritis of the knee.The Cochrane database of systematic reviews · 2015Pooled it
- Pooled it
- Are depression, anxiety and poor mental health risk factors for knee pain? A systematic review.BMC musculoskeletal disorders · 2014Pooled it
- A systematic review investigating the efficacy of laterally wedged insoles for medial knee osteoarthritis.Rheumatology international · 2013Pooled it
- Pooled it
- The impact of insole wedge height on knee alignment, joint space width, and patient-reported outcomes in medial knee OA.PloS one · 2026Trial
- A Study on the Effects of Lateral-Wedge Insoles on Plantar-Pressure Pattern for Medial Knee Osteoarthritis Using the Wearable Sensing Insole.Sensors (Basel, Switzerland) · 2022Trial
- Varus Knee Limits Pain Relief Effects of Laterally Wedged Insoles and Ankle-Foot Orthoses in Medial Knee Osteoarthritis.Journal of rehabilitation medicine · 2022Trial
- Trial
- The Efficacy of a Lateral Wedge Insole for Painful Medial Knee Osteoarthritis After Prescreening: A Randomized Clinical Trial.Arthritis & rheumatology (Hoboken, N.J.) · 2019Trial
- Short-term effects of customized arch support insoles on symptomatic flexible flatfoot in children: A randomized controlled trial.Medicine · 2018Trial
- Lateral wedges with and without custom arch support for people with medial knee osteoarthritis and pronated feet: an exploratory randomized crossover study.Journal of foot and ankle research · 2017Trial
- Ankle motion influences the external knee adduction moment and may predict who will respond to lateral wedge insoles?: an ancillary analysis from the SILK trial.Osteoarthritis and cartilage · 2015Trial
- Trial
- Lateral wedge insole for knee osteoarthritis: randomized clinical trial.Sao Paulo medical journal = Revista paulista de medicina · 2015Trial
- Do laterally wedged insoles or valgus braces unload the medial compartment of the knee in patients with osteoarthritis?Clinical orthopaedics and related research · 2015Trial
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effect of lateral wedge insoles compared with flat control insoles on improving symptoms and slowing structural disease progression in medial knee osteoarthritis.
designRandomised controlled trial.
settingCommunity in Melbourne, Australia.
participants200 people aged 50 or more with clinical and radiographic diagnosis of mild to moderately severe medial knee osteoarthritis.
interventionsFull length 5 degree lateral wedged insoles or flat control insoles worn inside the shoes daily for 12 months.
main outcome measuresPrimary symptomatic outcome was change in overall knee pain (past week) measured on an 11 point numerical rating scale. Primary structural outcome was change in volume of medial tibial cartilage from magnetic resonance imaging scans. Secondary clinical outcomes included changes in measures of pain, function, stiffness, and health related quality of life. Secondary structural outcomes included progression of medial cartilage defects and bone marrow lesions.
resultsBetween group differences did not differ significantly for the primary outcomes of change in overall pain (-0.3 points, 95% confidence intervals -1.0 to 0.3) and change in medial tibial cartilage volume (-0.4 mm(3), 95% confidence interval -15.4 to 14.6), and confidence intervals did not include minimal clinically important differences. None of the changes in secondary outcomes showed differences between groups.
conclusionLateral wedge insoles worn for 12 months provided no symptomatic or structural benefits compared with flat control insoles. Trial registration Australian New Zealand Clinical Trials Registry ACTR12605000503628 and ClinicalTrials.gov NCT00415259.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.