Evidence map›Paper›PMID 21592772›Full record

ReviewCurrent opinion in biotechnology2011

Applications of viral nanoparticles in medicine.

Ibrahim Yildiz, Sourabh Shukla, Nicole F Steinmetz

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals.Bioengineering (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Artificial viruses: A nanotechnology based approach.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Review
  10. Review
  11. Understanding Virus Structure and Dynamics through Molecular Simulations.Journal of chemical theory and computation · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. How promising are HIV-1-based virus-like particles for medical applications.Frontiers in cellular and infection microbiology · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ibrahim YildizDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
Sourabh Shukla
Nicole F Steinmetz

Funding

NEW FACULTY RECRUITMENT IMAGE-GUIDED CANCER THERAPEUTICSP30EB011317 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DUERK, JEFFREY L. · 2009 to 2010
$762k
Viral nanoparticles as platforms for the design of novel targeted therapeuticsR00EB009105 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI STEINMETZ, NICOLE FRANZISKA · 2010 to 2012
$728k
NIBIB NIH HHS P30 EB011317NIBIB NIH HHS R00 EB009105
6 · The paper itself

Abstract

Several nanoparticle platforms are currently being developed for applications in medicine, including both synthetic materials and naturally occurring bionanomaterials such as viral nanoparticles (VNPs) and their genome-free counterparts, virus-like particles (VLPs). A broad range of genetic and chemical engineering methods have been established that allow VNP/VLP formulations to carry large payloads of imaging reagents or drugs. Furthermore, targeted VNPs and VLPs can be generated by including peptide ligands on the particle surface. In this article, we highlight state-of-the-art virus engineering principles and discuss recent advances that bring potential biomedical applications a step closer. Viral nanotechnology has now come of age and it will not be long before these formulations assume a prominent role in the clinic.

Indexed as

Diagnostic ImagingGenetic EngineeringGenetic VectorsMolecular ImagingNanomedicineNanoparticlesVirion

Identifiers

PMID21592772
PMCPMC3206135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.