ArticleVirology journal2011
Comparison of phenotypes produced in response to transient expression of genes encoded by four distinct begomoviruses in Nicotiana benthamiana and their correlation with the levels of developmental miRNAs.
Article in Virology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
- Article
- Natural resistance of tomato plants to Tomato yellow leaf curl virus.Frontiers in plant science · 2022Review
- Host GRXC6 restricts Tomato yellow leaf curl virus infection by inhibiting the nuclear export of the V2 protein.PLoS pathogens · 2021Article
- Engineering tolerance to CLCuD in transgenic Gossypium hirsutum cv. HS6 expressing Cotton leaf curl Multan virus-C4 intron hairpin.Scientific reports · 2021Article
- Geminivirus-Host Interactions: Action and Reaction in Receptor-Mediated Antiviral Immunity.Viruses · 2021Review
- Geminiviral Triggers and Suppressors of Plant Antiviral Immunity.Microorganisms · 2021Review
- Stability of Begomoviral pathogenicity determinant βC1 is modulated by mutually antagonistic SUMOylation and SIM interactions.BMC biology · 2020Article
- Suppression of nbe-miR1919c-5p Expression inViruses · 2020Article
- Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle.Frontiers in plant science · 2020Review
- The Rep proteins encoded by alphasatellites restore expression of a transcriptionally silenced green fluorescent protein transgene inVirusdisease · 2019Article
- Plant Antiviral Immunity Against Geminiviruses and Viral Counter-Defense for Survival.Frontiers in microbiology · 2019Review
- Single amino acid in V2 encoded by TYLCV is responsible for its self-interaction, aggregates and pathogenicity.Scientific reports · 2018Article
- The six Tomato yellow leaf curl virus genes expressed individually in tomato induce different levels of plant stress response attenuation.Cell stress & chaperones · 2017Article
- Maintenance of Cotton Leaf Curl Multan Betasatellite byFrontiers in plant science · 2017Article
- Amplicon-Based RNA Interference Targeting V2 Gene of Cotton Leaf Curl Kokhran Virus-Burewala Strain Can Provide Resistance in Transgenic Cotton Plants.Molecular biotechnology · 2016Article
- Article
- Development of Cotton leaf curl virus resistant transgenic cotton using antisense ßC1 gene.Saudi journal of biological sciences · 2016Article
- CRISPR/Cas9: A Tool to Circumscribe Cotton Leaf Curl Disease.Frontiers in plant science · 2016Article
- Functional Analysis of Cotton Leaf Curl Kokhran Virus/Cotton Leaf Curl Multan Betasatellite RNA Silencing Suppressors.Biology · 2015Article
- Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhitefly-transmitted geminiviruses (begomoviruses) are a major limiting factor for the production of numerous dicotyledonous crops throughout the world. Begomoviruses differ in the number of components that make up their genomes and association with satellites, and yet they cause strikingly similar phenotypes, such as leaf curling, chlorosis and stunted plant growth. MicroRNAs (miRNAs) are small endogenous RNAs that regulate plant growth and development. The study described here was aimed at investigating the effects of each virus encoded gene on the levels of developmental miRNAs to identify common trends between distinct begomoviruses.
resultsAll genes encoded by four distinct begomoviruses (African cassava mosaic virus [ACMV], Cabbage leaf curl virus [CbLCuV], Tomato yellow leaf curl virus [TYLCV] and Cotton leaf curl virus/Cotton leaf curl betasatellite [CLCuV/CLCuMB]) were expressed from a Potato virus X (PVX) vector in Nicotiana benthamiana. Changes in the levels of ten miRNAs in response to the virus genes were determined by northern blotting using specific miRNA probes. For the monopartite begomoviruses (TYLCV and CLCuMV) the V2 gene product was identified as the major symptom determinant while for bipartite begomoviruses (ACMV and CbLCuV) more than one gene appears to contribute to symptoms and this is reflected in changes in miRNA levels. The phenotype induced by expression of the βC1 gene of the betasatellite CLCuMB was the most distinct and consisted of leaf curling, vein swelling, thick green veins and enations and the pattern of changes in miRNA levels was the most distinct.
conclusionsOur results have identified symptom determinants encoded by begomoviruses and show that developmental abnormalities caused by transient expression of begomovirus genes correlates with altered levels of developmental miRNAs. Additionally, all begomovirus genes were shown to modulate miRNA levels, the first time this has been shown to be the case.
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