Evidence map›Paper›PMID 21592251›Full record

ArticleAddiction (Abingdon, England)2011

The effect of neighborhood deprivation and residential relocation on long-term injection cessation among injection drug users (IDUs) in Baltimore, Maryland.

Becky L Genberg, Stephen J Gange, Vivian F Go, David D Celentano, Gregory D Kirk, Carl A Latkin, Shruti H Mehta

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Becky L GenbergBrown University, Program in Public Health, Providence, RI 02912, USA. bgenberg@jhsph.edu
Stephen J Gange
Vivian F Go
David D Celentano
Gregory D Kirk
Carl A Latkin
Shruti H Mehta

Funding

INCIDENCE OF HIV INFECTIONS IN A COHORT OF IV DRUG USERSR01DA012568 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MEHTA, SHRUTI H · 1999 to 2017
$15.5M
THE NATURAL HISTORY OF HIV INFECTION AMONG DRUG USERSR01DA004334 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KIRK, GREGORY D · 1987 to 2011
$7.6M
Natural History of HIV Infection In Injection Drug UsersR56DA004334 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KIRK, GREGORY D · 2012 to 2013
$3.2M
Long Term Injection Cessation among Injection Drug Users (IDUs)R36DA025501 · NIDA · JOHNS HOPKINS UNIVERSITY · PI GENBERG, BECKY LYNN · 2008 to 2009
$100k
NIDA NIH HHS R01 DA004334NIDA NIH HHS R01DA004334NIDA NIH HHS R01 DA012568NIDA NIH HHS R01DA012568NIDA NIH HHS R36 DA025501NIDA NIH HHS R36DA025501NIDA NIH HHS R56 DA004334
6 · The paper itself

Abstract

aimsTo determine the incidence of long-term injection cessation and its association with residential relocation and neighborhood deprivation.

designALIVE (AIDS Linked to the Intravenous Experience) is a prospective cohort with semi-annual follow-up since 1988. Multi-level discrete time-to-event models were constructed to investigate individual and neighborhood-level predictors of long-term injection cessation.

settingBaltimore, USA.

participantsA total of 1697 active injectors from ALIVE with at least eight semi-annual study visits. MEASUREMENTS: Long-term injection cessation was defined as 3 consecutive years without self-reported injection drug use.

findingsA total of 706 (42%) injectors achieved long-term cessation (incidence=7.6 per 100 person-years). After adjusting for individual-level factors, long-term injection cessation was 29% less likely in neighborhoods in the third quartile of deprivation [hazard ratio (HR)=0.71, 95% CI: 0.53, 0.95) and 43% less likely in the highest quartile of deprivation (HR=0.57, 95% CI: 0.43, 0.76) compared to the first quartile. Residential relocation was associated with increased likelihood of long-term injection cessation (HR=1.55, 95% CI: 1.31, 1.82); however, the impact of relocation varied depending on the deprivation in the destination neighborhood. Compared to those who stayed in less deprived neighborhoods, relocation from highly deprived to less deprived neighborhoods had the strongest positive impact on long-term injection cessation (HR=1.96, 95% CI: 1.50, 2.57), while staying in the most deprived neighborhoods was detrimental (HR=0.76, 95% CI: 0.63, 0.93).

conclusionsLong-term cessation of injection of opiates and cocaine occurred frequently following a median of 9 years of injection and contextual factors appear to be important. Our findings suggest that improvements in the socio-economic environment may improve the effectiveness of cessation programs.

Indexed as

Psychosocial DeprivationResidence CharacteristicsAdultBaltimoreBlack or African AmericanChronic DiseaseDrug UsersEpidemiologic MethodsFemaleHealth ServicesHIV InfectionsHumansMaleSocioeconomic FactorsSubstance Abuse, IntravenousTime Factors

Identifiers

PMID21592251
PMCPMC3189272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.