ArticleOrganic letters2011
Highly stereoselective Brønsted acid catalyzed synthesis of spirooxindole pyrans.
Article in Organic letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 70 citations in OpenAlex.
- An Enantioselective Cross-Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans.Journal of the American Chemical Society · 2018Article
- A Biocatalytic Route to Highly Enantioenriched β-Hydroxydioxinones.Advanced synthesis & catalysis · 2017Article
- Molecular diversity of spirooxindoles. Synthesis and biological activity.Molecular diversity · 2016Review
- Catalytic enantioselective synthesis of 2-aryl-chromenes.Chemical science · 2014Article
- Highly Efficient and Stereoselective Construction of Bispirooxindole Derivatives via a Three-Component 1,3-Dipolar Cycloaddition Reaction.ChemistryOpen · 2014Article
- Asymmetric Aldol Reaction of 3-Acetyl-2Advanced synthesis & catalysis · 2014Article
- An N-heterocyclic carbene/Lewis acid strategy for the stereoselective synthesis of spirooxindole lactones.Angewandte Chemie (International ed. in English) · 2012Article
- Bi(OTf)3-, TfOH-, and TMSOTf-mediated, one-pot epoxide rearrangement, addition, and intramolecular silyl-modified Sakurai (ISMS) cascade toward dihydropyrans: comparison of catalysts and role of Bi(OTf)3.The Journal of organic chemistry · 2011Article
- Enantioselective Pictet-Spengler Reactions of Isatins for the Synthesis of Spiroindolones.Tetrahedron letters · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A Brønsted acid-catalyzed Prins-type cyclization sequence to construct spirooxindole pyrans in high yields and excellent diastereoselectivity has been developed. The combination of a β-hydroxy dioxinone fragment and isatin dimethyl acetal generate oxa-spirooxindoles efficiently. These compounds are diversifiable scaffolds that tap into the rich chemistry of dioxinones.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.