Evidence map›Paper›PMID 21591746›Full record

ArticleInorganic chemistry2011

Design and synthesis of a bombesin peptide-conjugated tripodal phosphino dithioether ligand topology for the stabilization of the fac-[M(CO)3]+ core (M=(99 m)Tc or Re).

Raghuraman Kannan, Nagavarakishore Pillarsetty, Hariprasad Gali, Timothy J Hoffman, Charles L Barnes, Silvia S Jurisson, Charles J Smith, Wynn A Volkert

Abstract read
In one paragraph

Article in Inorganic chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Optimal His-Tag Design for Efficient [Bioconjugate chemistry · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raghuraman KannanDepartment of Radiology, University of Missouri, Columbia, Missouri 65211, USA. kannanr@health.missouri.edu
Nagavarakishore Pillarsetty
Hariprasad Gali
Timothy J Hoffman
Charles L Barnes
Silvia S Jurisson
Charles J Smith
Wynn A Volkert

Funding

CENTER FOR SINGLE PHOTON-EMITTING CANCER IMAGING AGENTSP50CA103130 · NCI · UNIVERSITY OF MISSOURI-COLUMBIA · PI VOLKERT, WYNN A · 2003 to 2007
$9.8M
NCI NIH HHS P50 CA103130
6 · The paper itself

Abstract

A new tumor-seeking tridentate topology consisting of a phosphino dithioether ((HOCH(2))(2)PCH(2)CH(2)S(CH(2))(n)CH(2)SR; PS(2)) ligand framework for the production of kinetically inert and in vivo stable facial [(99m)Tc(CO)(3)(PS(2))](+) or [Re(CO)(3)(PS(2))](+) is described. The X-ray crystal structure of fac-Re(CO)(3)(PS(2))PF(6) is reported. The bioconjugation strategies for incorporating bombesin (BBN) peptides on to the PS(2) tripodal framework and, thereby, de novo designing of GRP receptor-seeking Tc(PS(2)-BBN)(CO)(3) are developed.

Indexed as

BombesinCarbon MonoxideCrystallography, X-RayKineticsLigandsModels, MolecularMolecular StructureOrganometallic CompoundsRheniumStereoisomerismSulfhydryl CompoundsTechnetiumBombesinCarbon MonoxideLigandsOrganometallic CompoundsRheniumSulfhydryl CompoundsTechnetium

Identifiers

PMID21591746
PMCPMC4432846

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.