Evidence map›Paper›PMID 21590810›Full record

ArticleYeast (Chichester, England)2011

A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion.

Joo Y Hong, Vidhu Mathur, Susan W Liebman

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Yeast (Chichester, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Prions in yeast.Genetics · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joo Y HongLaboratory for Molecular Biology, Department of Biological Sciences, University of Illinois at Chicago, Chicago, USA.
Vidhu Mathur
Susan W Liebman
University of Illinois Chicago · US

Funding

YEAST PRION FACTOR (PSI+)R01GM056350 · NIGMS · UNIVERSITY OF NEVADA RENO · PI LIEBMAN, SUSAN W · 1997 to 2018
$6.6M
NIGMS NIH HHS GM56350NIGMS NIH HHS R01 GM056350
6 · The paper itself

Abstract

Most scoring assays for yeast prions are dependent on specific genetic markers and constructs that differ for each prion. Here we describe a simple colour assay for the [URE3] prion that works in the 74D-964 strain frequently used to score the [PSI(+)] prion. Although this assay can only be used to score for [URE3] in the [psi(-)] version of the strain, it makes it easier to examine the effects of host mutations or environmental changes on [URE3] or [PSI(+)] using a colour assay in the identical genetic background.

Indexed as

ColorimetryGlutathione PeroxidaseMutationPeptide Termination FactorsPrionsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsGlutathione PeroxidasePeptide Termination FactorsPrionsSaccharomyces cerevisiae ProteinsSUP35 protein, S cerevisiaeURE2 protein, S cerevisiae

Identifiers

PMID21590810
PMCPMC3379880
OpenAlexW2043297781

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.