ArticleJournal of molecular evolution2011
Characterization and evolution of MHC class II B genes in Ardeid birds.
Article in Journal of molecular evolution, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 30 citations in OpenAlex.
- Allelic diversity and selection at the MHC class I and class II in a long-distance migratory shorebird, the Hudsonian Godwit (Limosa haemastica).Immunogenetics · 2026Article
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- Distinct evolutionary trajectories of MHC class I and class II genes in Old World finches and buntings.Heredity · 2021Article
- Ovine CD14- an Immune Response Gene Has a Role Against Gastrointestinal NematodeFrontiers in immunology · 2021Article
- Polymorphism of MHC class IIB in an acheilognathid species, Rhodeus sinensis shaped by historical selection and recombination.BMC genetics · 2019Article
- Polymorphism in the major histocompatibility complex (MHC class II B) genes of the Rufous-backed Bunting (PeerJ · 2017Article
- Diversity and selection of MHC class I genes in the vulnerable Chinese egret (Egretta eulophotes).PloS one · 2017Article
- Major histocompatibility complex class II DAB alleles associated with intestinal parasite load in the vulnerable Chinese egret (Egretta eulophotes).Ecology and evolution · 2016Article
- Isolation and characterization of major histocompatibility complex class II B genes in cranes.Immunogenetics · 2015Article
- Characterization of a non-classical MHC class II gene in the vulnerable Chinese egret (Egretta eulophotes).Immunogenetics · 2015Article
- Trans-Species Polymorphism in Immune Genes: General Pattern or MHC-Restricted Phenomenon?Journal of immunology research · 2015Review
- Extraordinary MHC class II B diversity in a non-passerine, wild bird: the Eurasian Coot Fulica atra (Aves: Rallidae).Ecology and evolution · 2014Article
- Structure and polymorphism of the major histocompatibility complex class II region in the Japanese Crested Ibis, Nipponia nippon.PloS one · 2014Article
- MHC class II B diversity in blue tits: a preliminary study.Ecology and evolution · 2013Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Major histocompatibility complex (MHC) is a multi-gene family that is very suitable to investigate a wide range of open questions in evolutionary ecology. In this study, we characterized two expressed MHC class II B genes (DAB1 and DAB2) in the Grey Heron (Aves: Ardea cinerea). We further developed the primer pairs to amplify and sequence two MHC class II B loci in ten ardeid birds. Phylogenetic analysis revealed that different parts of the genes showed different evolutionary patterns. The exon 2 sequences tended to cluster two gene-specific lineages. In each lineage, exon 2 sequences from several species showed closer relationships than sequences within species, and two shared identical alleles were found between species (Egretta sacra and Nycticorax nycticorax; Egretta garzetta and Bubulcus ibis), supporting the hypothesis of trans-species polymorphism. In contrast, the species-specific intron 2 plus partial exon 3 tree suggested that DAB1 and DAB2 were subject to concerted evolution. GENECONV analyses showed the gene exchange played an important role in the ardeid MHC evolution.
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