Evidence map›Paper›PMID 21590280›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2011

Will early reconstruction prevent abnormal kinematics after ACL injury? Two-year follow-up using dynamic radiostereometry in 14 patients operated with hamstring autografts.

Jonas Isberg, Eva Faxén, Gauti Laxdal, Bengt I Eriksson, Johan Kärrholm, Jon Karlsson

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biomechanical techniques to evaluate tibial rotation. A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2012
    Pooled it
  2. No risk of arthrofibrosis after acute anterior cruciate ligament reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018
    Trial
  3. Trial
  4. Biomechanics and Outcomes of Modern Tibial Polyethylene Inserts.Current reviews in musculoskeletal medicine · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Static and dynamic tibial translation before, 5 weeks after, and 5 years after anterior cruciate ligament reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The effect of distal femur bony morphology on in vivo knee translational and rotational kinematics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2012
    Article
  15. Static rotational knee laxity in anterior cruciate ligament injuries.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2012
    Review
  16. Dynamic knee laxity measurement devices.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2012
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonas IsbergDepartment of Orthopaedics, Sahlgrenska University Hospital/Mölndal, 413 80, Mölndal, Sweden. Jonas.isberg@vgregion.se
Eva Faxén
Gauti Laxdal
Bengt I Eriksson
Johan Kärrholm
Jon Karlsson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevious studies have reported that Anterior Cruciate Ligament (ACL) reconstruction does not restore normal tibial rotation in patients with chronic instability and repeated episodes of giving way. We hypothesised that early ACL reconstruction, using quadruple hamstring autografts, before the pivoting episodes had occurred, would protect the knee joint from developing abnormal kinematics with increased external tibial rotation during flexion.

methodsFourteen consecutive patients (8 men, 6 women) with a median age of 24 years (18-43), with a complete, isolated unilateral ACL rupture and an intact contralateral knee, were studied. The operations were performed by one experienced surgeon, using quadruple hamstring autografts. We used dynamic radiostereometry (RSA) with tantalum markers inserted in both the injured and the intact contralateral knee to study the pattern of knee motion during active and weight-bearing knee extension. The patients were evaluated pre-operatively and followed for 2 years after the ACL reconstruction. The anterior-posterior laxity was measured using the KT-1000.

resultsBefore surgical repair of the ACL, the internal/external tibial rotation or abduction/adduction did not differ significantly between the injured and intact knees (P = 0.27-0.91). Separate studies of the anterior-posterior translation of the medial and lateral femoral flexion facet centres (MFC and LFC) relative to a fixed tibia did not reveal any significant differences between the injured and intact knees (P = 0.21-0.59). Pre-operatively, the KT-1000 laxity measurements showed a side-to-side difference of 2.5 (1.0-5.5) mm. At 2 years, the laxity side-to-side difference was 0.5 (0-3.0) mm (P = 0.001), and there were still no significant differences between the injured and intact knees in terms of internal/external tibial rotation and abduction/adduction (P = 0.13-0.60). Nor did the anterior-posterior translation of the flexion facet centres differs (P = 0.27-0.97).

conclusionDuring the first 6-8 weeks after the ACL injury, before pivoting episodes had occurred, the kinematics of the injured knee were normal and did not differ from those of the intact contralateral knee. Reconstruction of the ACL within 10 weeks after injury using quadruple hamstring autografts resulted in unchanged knee kinematics for 2 years and no difference compared with the intact contralateral knee. Surgical repair during the early phase after the injury appears to protect the knee from developing abnormal knee motion after an ACL rupture. LEVEL OF EVIDENCE: III.

Indexed as

AdolescentAdultAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaFemaleFollow-Up StudiesHumansJoint InstabilityKnee InjuriesMaleProspective StudiesRadiostereometric AnalysisSecondary PreventionTendons

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.