ArticlePediatric reports2010
Intraosseous fluid resuscitation in meningococcal disease and lower limb injury.
Article in Pediatric reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Intraosseous access in neurological emergencies: a critical narrative review and research framework.Future science OA · 2026Review
- Intramuscular hemorrhage and fluid extravasation into the anterior compartment secondary to intraosseous resuscitation, the "Nicked-Cortex" sign.Radiology case reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We set out to review the recent incidence of extravasation and compartment syndrome in children with meningococcal disease admitted to our Paediatric Intensive Care Unit (PICU) who had been resuscitated with intraosseous (IO) needles. Over a 12-month period, 18 children were admitted to PICU with meningococcal sepsis. Four of these children were resuscitated with IO needles and 2 developed serious complications as a result of extravasation and compartment syndrome. Clinical practice guidelines for children with severe sepsis advocate aggressive early fluid resuscitation therapy. We have identified extravasation and lower limb injury as a potential issue of increasing concern with appropriate aggressive IO fluid resuscitation in severe septic shock in children. Powered IO access systems such as the EZ-IO system offer advantages in terms of placement speed, accuracy and bone entry site profile at minimal extra financial cost.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.