Evidence map›Paper›PMID 21586503›Full record

ArticleThe British journal of radiology2012

Bone age assessment by dual-energy X-ray absorptiometry in children: an alternative for X-ray?

D H M Heppe, H R Taal, G D S Ernst, E L T Van Den Akker, M M H Lequin, A C S Hokken-Koelega, J J M Geelhoed, V W V Jaddoe

Open access · greenAbstract readValidation Study
In one paragraph

Article in The British journal of radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

D H M HeppeThe Generation R Study Group, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.
H R Taal
G D S Ernst
E L T Van Den Akker
M M H Lequin
A C S Hokken-Koelega
J J M Geelhoed
V W V Jaddoe
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to validate dual-energy X-ray absorptiometry (DXA) as a method to assess bone age in children.

methodsPaired dual-energy X-ray absorptiometry (DXA) scans and X-rays of the left hand were performed in 95 children who attended the paediatric endocrinology outpatient clinic of University Hospital Rotterdam, the Netherlands. We compared bone age assessments by DXA scan with those performed by X-ray. Bone age assessment was performed by two blinded observers according to the reference method of Greulich and Pyle. Intra-observer and interobserver reproducibility were investigated using the intraclass correlation coefficient (ICC), and agreement was tested using Bland and Altman plots.

resultsThe intra-observer ICCs for both observers were 0.997 and 0.991 for X-ray and 0.993 and 0.987 for DXA assessments. The interobserver ICC was 0.993 and 0.991 for X-ray and DXA assessments, respectively. The mean difference between bone age assessed by X-ray and DXA was 0.11 years. The limits of agreement ranged from -0.82 to 1.05 years, which means that 95% of all differences between the methods were covered by this range.

conclusionsResults of bone age assessment by DXA scan are similar to those obtained by X-ray. The DXA method seems to be an alternative for assessing bone age in a paediatric hospital-based population.

Indexed as

Hand BonesAbsorptiometry, PhotonAdolescentAge Determination by SkeletonAge FactorsBone DensityBone DevelopmentChildChild, PreschoolFemaleHandHumansInfantInfant, NewbornMaleObserver Variation

Identifiers

PMID21586503
PMCPMC3473959
OpenAlexW1983561335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.