ArticleBioanalysis2011
New approaches in the detection of calcium-containing microcrystals in synovial fluid.
Article in Bioanalysis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- An Update on the Diagnosis and Management of Calcium Crystal Disease.Current rheumatology reports · 2023Review
- Physical attributes of salivary calcium particles and their interaction with gingival epithelium.Biomedical journal · 2021Article
- Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis.Journal of visualized experiments : JoVE · 2021Article
- Amentadione from the AlgaMarine drugs · 2020Article
- Nonlinear optical microscopy is a novel tool for the analysis of cutaneous alterations in pseudoxanthoma elasticum.Lasers in medical science · 2020Article
- Dietary Oxalate Induces Urinary Nanocrystals in Humans.Kidney international reports · 2020Article
- Correlation between synovial fluid calcium containing crystal estimation and varying grades of osteoarthritis created using a rabbit model: Potential diagnostic tool.Journal of clinical orthopaedics and trauma · 2020Article
- A novel fluorescein-bisphosphonate based diagnostic tool for the detection of hydroxyapatite in both cell and tissue models.Scientific reports · 2018Article
- Restriction of Passive Glenohumeral Abduction Combined With Normal Passive External Rotation Is a Diagnostic Feature of Calcific Tendinitis.Orthopaedic journal of sports medicine · 2018Article
- Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis.Cellular and molecular life sciences : CMLS · 2016Article
- Nanoparticle Tracking Analysis for the Enumeration and Characterization of Mineralo-Organic Nanoparticles in Feline Urine.PloS one · 2016Article
- Calcific tendinitis of the rotator cuff: a review.Journal of clinical and diagnostic research : JCDR · 2013Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe presence of calcium phosphate crystals such as basic calcium phosphate and calcium pyrophosphate dihydrate in intra-articular fluid is linked to a number of destructive arthropathies and detection of these deposits is often pivotal for early diagnosis and appropriate management of such disease.
resultsWe describe the use of a calcium-sensitive dye, Fluo-4, to selectively label calcium-containing mineral deposits in synovial fluid, which can then be easily visualized using a standard fluorescence microscope. Furthermore, we have combined the fluorescent properties of the tagged crystals with flow cytometry as a fast and semi-quantitative method of detection.
conclusionDot-plots were used to quantify differences between various types of arthropathies and confirmed by visual observation of the crystals under a fluorescence microscope.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.