SynthesisInternational archives of occupational and environmental health2012
The role of psychosocial stress at work for the development of cardiovascular diseases: a systematic review.
Synthesis in International archives of occupational and environmental health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 12 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
173 citing papers in PubMed, 12 syntheses or guidelines pooled it, 468 citations in OpenAlex.
- The demands-control-support work stress model and risk of ischemic heart disease: causal inference based on observational epidemiology.Scandinavian journal of work, environment & health · 2026Pooled it
- Pooled it
- Analysis of Work Related Factors, Behavior, Well-Being Outcome, and Job Satisfaction of Workers of Emergency Medical Service: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Occupational Physical Activity and Lung Cancer Risk: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Analysis of Job-Related Demands and Resources in Ambulatory Youth Welfare Services: A Qualitative and Quantitative Approach.International journal of environmental research and public health · 2020Pooled it
- Basal cortisol, cortisol reactivity, and telomere length: A systematic review and meta-analysis.Psychoneuroendocrinology · 2019Pooled it
- Computer-based versus in-person interventions for preventing and reducing stress in workers.The Cochrane database of systematic reviews · 2017Pooled it
- Effort-Reward Imbalance at Work and Incident Coronary Heart Disease: A Multicohort Study of 90,164 Individuals.Epidemiology (Cambridge, Mass.) · 2017Pooled it
- Perceived job insecurity, unemployment and depressive symptoms: a systematic review and meta-analysis of prospective observational studies.International archives of occupational and environmental health · 2016Pooled it
- Measuring allostatic load in the workforce: a systematic review.Industrial health · 2015Pooled it
- Occupational stress and subclinical atherosclerosis: a systematic review.International journal of occupational and environmental health · 2014Pooled it
- Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2013Pooled it
- Improvements in stress among Latinas participating in a randomized controlled trial of technology-supported physical activity interventions.Stress and health : journal of the International Society for the Investigation of Stress · 2024Trial
- Health Care Workers' Need for Headspace: Findings From a Multisite Definitive Randomized Controlled Trial of an Unguided Digital Mindfulness-Based Self-help App to Reduce Healthcare Worker Stress.JMIR mHealth and uHealth · 2022Trial
- Job Satisfaction and Chronic Stress of General Practitioners and Their Teams: Baseline Data of a Cluster-Randomised Trial (IMPROVEInternational journal of environmental research and public health · 2021Trial
- Financial strain and ideal cardiovascular health in middle-aged and older women: Data from the Women's health study.American heart journal · 2019Trial
- The Effect of Heart Rate Variability Biofeedback Training on Mental Health of Pregnant and Non-Pregnant Women: A Randomized Controlled Trial.International journal of environmental research and public health · 2019Trial
- Does Physiological Stress Slow Down Wound Healing in Patients With Diabetes?Journal of diabetes science and technology · 2017Trial
- Efficacy and cost-effectiveness of a web-based and mobile stress-management intervention for employees: design of a randomized controlled trial.BMC public health · 2013Trial
- Identifying stress-relevant events in everyday nursing practice using psychophysiological outcomes - an observational multimethod study.BMC nursing · 2026Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA systematic review was carried out to assess evidence for the association between different models of stress at work, and cardiovascular morbidity and mortality.
methodsA literature search was conducted using five databases (MEDLINE, Cochrane Library, EMBASE, PSYNDEX and PsycINFO). Inclusion criteria for studies were the following: self-reported stress for individual workplaces, prospective study design and incident disease (myocardial infarction, stroke, angina pectoris, high blood pressure). Evaluation, according to the criteria of the Scottish Intercollegiate Guidelines Network, was done by two readers. In case of disagreement, a third reader was involved.
resultsTwenty-six publications were included, describing 40 analyses out of 20 cohorts. The risk estimates for work stress were associated with a statistically significant increased risk of cardiovascular disease in 13 out of the 20 cohorts. Associations were significant for 7 out of 13 cohorts applying the demand-control model, all three cohorts using the effort-reward model and 3 out of 6 cohorts investigating other models. Most significant results came from analyses considering only men. Results for the association between job stress and cardiovascular diseases in women were not clear. Associations were weaker in participants above the age of 55.
conclusionsIn accordance with other systematic reviews, this review stresses the importance of psychosocial factors at work in the aetiology of cardiovascular diseases. Besides individual measures to manage stress and to cope with demanding work situations, organisational changes at the workplace need to be considered to find options to reduce occupational risk factors for cardiovascular diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.