Evidence map›Paper›PMID 21584673›Full record

ArticleNeuroradiology2012

Hyperdense basilar artery sign-a reliable sign of basilar artery occlusion.

Lara Connell, Inga Katharina Koerte, Ruediger Paul Laubender, Dominik Morhard, Jennifer Linn, Hans Christoph Becker, Maximilian Reiser, Hartmut Brueckmann, Birgit Ertl-Wagner

Abstract read
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In one paragraph

Article in Neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

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  9. Correlation between clot density and recanalization success or stroke etiology in acute ischemic stroke patients.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017
    Article
  10. Review
  11. The hyperdense basilar artery sign: a case of locked-in syndrome.International journal of emergency medicine · 2016
    Article
  12. Review
  13. Article
  14. Article
  15. Basilar Occlusion Syndromes: An Update.The Neurohospitalist · 2015
    Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lara ConnellInstitute of Clinical Radiology, Ludwig-Maximilians-University, Grosshadern Campus, Marchioninistr. 15, 81377 Munich, Germany.
Inga Katharina Koerte
Ruediger Paul Laubender
Dominik Morhard
Jennifer Linn
Hans Christoph Becker
Maximilian Reiser
Hartmut Brueckmann
Birgit Ertl-Wagner
Ludwig-Maximilians-Universität München · DEZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to investigate the value of the hyperdense basilar artery (HBA) sign and of basilar artery (BA) attenuation measurements as predictors of basilar artery occlusion (BAO) on nonenhanced cranial CT (NECT).

methodsForty-one consecutive patients with proven BAO in CT angiography, who had undergone NECT for initial evaluation (30 males, 11 females) were retrospectively included. Another 41 age-matched patients without BAO were included as a control group. The NECT scans of both groups were assessed by three independent blinded readers (staff, fellow, and resident) in a randomized reading order using a standardized semiquantitative questionnaire. Visual BA hyperdensity, including the presence of HBA sign (hyperdensity scores of 4 and 5/5), was assessed, quantitative BA attenuation was measured in a region of interest (ROI), and diagnosis of BAO was made before and after ROI measurements. For statistical analysis, multivariate mixed effects models, likelihood ratio tests, and receiver operating characteristics techniques were applied.

resultsHBA sign had a relatively low sensitivity (60.98-65.85%), specificity (70.73-90.24%), and accuracy (65.85-75.61%) for the presence/absence of BAO on NECT. Optimal cut-off points were 40-42 HU (sensitivity, 68.29-78.05%; specificity, 75.61-82.93%; accuracy, 74.39-80.49%).

conclusionIn basilar artery occlusion, quantitative measurement of BA attenuation can slightly improve the diagnostic predictiveness of NECT. However, even with optimal cut-off values, the sensitivity is too low to serve as the sole diagnostic decision-making tool.

Indexed as

AgedAged, 80 and overArterial Occlusive DiseasesBasilar ArteryCase-Control StudiesCerebral AngiographyFemaleHumansLikelihood FunctionsMaleMiddle AgedRegression AnalysisRetrospective StudiesROC CurveSensitivity and SpecificitySurveys and Questionnaires

Identifiers

PMID21584673
OpenAlexW1970540507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.