ArticleWorld journal of gastrointestinal pharmacology and therapeutics2010
Treatment of psychological co-morbidities in common gastrointestinal and hepatologic disorders.
Article in World journal of gastrointestinal pharmacology and therapeutics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 19 citations in OpenAlex.
- A Review of Inflammatory Bowel Disease: A Model of Microbial, Immune and Neuropsychological Integration.Public health reviews · 2021Review
- Effects of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Gut Microbiota in a Rat Model of Depression.Clinical pharmacology and translational medicine · 2019Article
- Ketamine interactions with gut-microbiota in rats: relevance to its antidepressant and anti-inflammatory properties.BMC microbiology · 2018Article
- Psychological issues in inflammatory bowel disease: an overview.Gastroenterology research and practice · 2012Article
- Psychopharmacological treatment and psychological interventions in irritable bowel syndrome.Gastroenterology research and practice · 2012Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety and depressive disorders frequently coexist with gastrointestinal and hepatologic conditions. Despite their high prevalence, approach to treating these co-morbidities is not always straightforward. This paper aims to review the current literature into etiology of psychological co-morbidities and their treatment in three conditions commonly encountered at gastroenterology outpatient clinics, namely inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and chronic hepatitis C (HepC). The paper demonstrates that although psychotherapy (and cognitive-behavioural therapy in particular) has been established as an effective treatment in IBS, more studies are needed in HepC and IBD. Antidepressants have been recognized as an effective treatment for psychological and somatic symptoms in IBS and for depression in HepC, but good quality studies in IBD are lacking despite the promising preliminary findings from animal models and case studies. Further studies in this area are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.