ArticleAntimicrobial agents and chemotherapy2011
Antifungal therapy in an athymic murine model of chromoblastomycosis by Fonsecaea pedrosoi.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- In Vitro Activities of Five Antifungal Drugs Against Conidia and Sclerotic Cells of Chromoblastomycosis Agent Fonsecaea spp.Microbiology and immunology · 2026Article
- Chromoblastomycosis caused byFrontiers in medicine · 2024Article
- Muriform Cells Can Reproduce by Dividing in an Athymic Murine Model of Chromoblastomycosis due toThe American journal of tropical medicine and hygiene · 2020Article
- [Long-pulsed 1064 nm Nd: YAG laser combined with terbinafine against chromoblastomycosis caused byNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
- Combination of Amphotericin B and Terbinafine against Melanized Fungi Associated with Chromoblastomycosis.Antimicrobial agents and chemotherapy · 2018Article
- Black yeasts and their filamentous relatives: principles of pathogenesis and host defense.Clinical microbiology reviews · 2014Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have compared the efficacy of terbinafine (TRB) and itraconazole (ITZ), the recommended drugs for the treatment of chromoblastomycosis, with that of posaconazole (PSC) and voriconazole (VRC) in athymic mice infected with the fungus Fonsecaea pedrosoi. Three weeks after challenge, mice were treated for 4 months with PSC at 10 or 20 mg/kg of body weight/day, with VRC at 10 or 20 mg/kg/day, with ITZ at 25 or 50 mg/kg/day, or with TRB at 150 or 250 mg/kg/day. The progress of the infection was evaluated by measuring the size of the lesions, by histopathological studies, and by cultures of the excised tissue. The two doses of PSC followed by the highest doses of ITZ and TRB showed the best results while VRC did not show efficacy. PSC could be an alternative in the treatment of chromoblastomycosis.
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Registered trials
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