ArticleGenes & development2011
Polycomb-mediated repression during terminal differentiation: what don't you want to be when you grow up?
Article in Genes & development, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Metabolic stress-induced long ncRNA transcription governs the formation of meiotic DNA breaks in the fission yeast fbp1 gene.PloS one · 2024Article
- The PRC2 complex directly regulates the cell cycle and controls proliferation in skeletal muscle.Cell cycle (Georgetown, Tex.) · 2020Article
- JARID2 and the PRC2 complex regulate the cell cycle in skeletal muscle.The Journal of biological chemistry · 2019Article
- JARID2 and the PRC2 complex regulate skeletal muscle differentiation through regulation of canonical Wnt signaling.Epigenetics & chromatin · 2018Article
- Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1.Scientific reports · 2016Article
- Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation.Developmental biology · 2015Article
- Epigenomic footprints across 111 reference epigenomes reveal tissue-specific epigenetic regulation of lincRNAs.Nature communications · 2015Article
- Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.The EMBO journal · 2014Article
- Interferon-γ resets muscle cell fate by stimulating the sequential recruitment of JARID2 and PRC2 to promoters to repress myogenesis.Science signaling · 2013Article
- The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state.Nucleic acids research · 2013Article
- Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression.Developmental dynamics : an official publication of the American Association of Anatomists · 2013Article
- Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.Epigenomics · 2012Review
- Article
- EZH2: a pivotal regulator in controlling cell differentiation.American journal of translational research · 2012Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Chromatin-modifying enzymes are known to be critical components for the correct differentiation of embryonic stem cells into specific lineages, such as neurons. Recently, the role of Polycomb group proteins has been studied in the specification and differentiation of muscle stem cells. In this perspective, we review a recent study by Juan and colleagues (pp. 789-794) in Genes & Development of the role of the polycomb group protein Ezh2 in muscle stem cells, and discuss the implications for general lineage restriction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.