ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2011
Introduction to placebo effects in medicine: mechanisms and clinical implications.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 82 citations in OpenAlex.
- Predictors of symptom improvement in patients with chronic coronary syndrome after percutaneous coronary intervention.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Trial
- The effects of low-level laser therapy on muscle strength and functional outcomes in individuals with knee osteoarthritis: a double-blinded randomized controlled trial.Scientific reports · 2023Trial
- Adjunctive Bright Light Therapy for Non-Seasonal Major Depressive Disorder: A Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Psilocybin microdosing does not affect emotion-related symptoms and processing: A preregistered field and lab-based study.Journal of psychopharmacology (Oxford, England) · 2022Trial
- Randomised controlled trials may underestimate drug effects: balanced placebo trial design.PloS one · 2014Trial
- Trial
- A narrative review of the placebo effect: historical roots, current applications, and emerging insights.European journal of clinical pharmacology · 2025Review
- Myths and Truths about Placebo Effect in Rehabilitation for Musculoskeletal Pain.Advances in therapy · 2021Article
- Precision medicine reaching out to the patients in allergology - a German-Japanese workshop report.Allergologie select · 2021Article
- A novel role of oxytocin: Oxytocin-induced well-being in humans.Biophysics and physicobiology · 2019Article
- What techniques might be used to harness placebo effects in non-malignant pain? A literature review and survey to develop a taxonomy.BMJ open · 2017Review
- Possible contribution of quantum-like correlations to the placebo effect: consequences on blind trials.Theoretical biology & medical modelling · 2017Article
- Does the model of additive effect in placebo research still hold true? A narrative review.JRSM open · 2017Article
- Measuring nonspecific factors in treatment: item banks that assess the healthcare experience and attitudes from the patient's perspective.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- The placebo effect in asthma.Current allergy and asthma reports · 2014Review
- The placebo effect in allergen-specific immunotherapy trials.Clinical and translational allergy · 2013Article
- Naltrexone may block euphoria-like placebo effect.BMJ case reports · 2013Article
- An exploration of the relationship between placebo and homeopathy and the implications for clinical trial design.JRSM short reports · 2013Review
- Local biologies and HIV/AIDS in highlands Papua, Indonesia.Culture, medicine and psychiatry · 2013Article
- Placebo effects: a new paradigm and relevance to psychiatry.International psychiatry : bulletin of the Board of International Affairs of the Royal College of Psychiatrists · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The field of placebo research has made considerable progress in the last years and it has become a major focus of interest. We know now that the placebo effect is a real neurobiological phenomenon and that the brain's 'inner pharmacy' is a critical determinant for the occurrence of psychobiological and behavioural changes relevant to healing processes and well-being. However, harnessing the advantages of placebo effects in healthcare is still a challenge. The first part of the theme issue summarizes and discusses the various kinds of placebo mechanisms across medical fields, thereby not only focusing on two main explanatory models-expectation and conditioning theory-but also taking into account empathy and social learning, emotion and motivation, spirituality and the healing ritual. The second part of the issue focuses on questions related to transferring knowledge from placebo research into clinical practice and discusses implications for the design and interpretation of clinical trials, for the therapeutic settings in daily patient care, and for future translational placebo research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.