ArticleBMC molecular biology2011
GhMPK16, a novel stress-responsive group D MAPK gene from cotton, is involved in disease resistance and drought sensitivity.
Article in BMC molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46 citing papers in PubMed, 122 citations in OpenAlex.
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- MITOGEN-ACTIVATED PROTEIN KINASE9 fine-tunes hypoxia signaling by phosphorylating ERF-VII transcription factors in Arabidopsis.The New phytologist · 2026Article
- Identification of SNPs and Candidate Genes Associated with Major Drought Tolerance QTL on Wheat Chromosome 4A.Plants (Basel, Switzerland) · 2026Article
- Molecular networks and signaling pathways governing abiotic stress tolerance in cotton: advances and perspectives.Functional & integrative genomics · 2026Review
- Multi-omics reveals DEAD-box RNA helicase 20 as key protein enhancing wilt resistance in transgenic chickpea.Plant cell reports · 2025Article
- Ectopic Over-Expression ofPlants (Basel, Switzerland) · 2025Article
- Mitogen-activated protein kinase (MAPK) gene family identification reveals GhMPK10-mediated regulation of abiotic stress tolerance through protein kinase signaling cascades in cotton.BMC plant biology · 2025Article
- GhMPK9-GhRAF39_1-GhWRKY40a Regulates the GhERF1b- and GhABF2-Mediated Pathways to Increase Cotton Disease Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Genome Identification of the Tea Plant (Genes · 2023Article
- Harnessing the role of mitogen-activated protein kinases against abiotic stresses in plants.Frontiers in plant science · 2023Review
- Systematic analysis of Histidine photosphoto transfer gene family in cotton and functional characterization in response to salt and around tolerance.BMC plant biology · 2022Article
- Defense Mechanisms of CottonInternational journal of molecular sciences · 2022Review
- Transcriptomic Analysis to Unravel Potential Pathways and Genes Involved in Pecan (International journal of molecular sciences · 2022Article
- Impact of water deficiency on leaf cuticle lipids and gene expression networks in cotton (Gossypium hirsutum L.).BMC plant biology · 2022Article
- Expression profiling of the mitogen-activated protein kinase gene family reveals their diverse response pattern in two different salt-tolerant Glycyrrhiza species.Genes & genomics · 2022Article
- Characterization of walnutFrontiers in plant science · 2022Article
- Mitogen-activated protein kinase action in plant response to high-temperature stress: a mini review.Protoplasma · 2021Review
- Regulatory Network of Cotton Genes in Response to Salt, Drought and Wilt Diseases (Frontiers in plant science · 2021Review
- Protein Kinase Signaling Pathways in Plant-Frontiers in plant science · 2021Review
- Cloning, Genetic Transformation and Cellular Localization of Abiotic Stress Responsive Universal Stress Protein Gene (GUSP1) inIranian journal of biotechnology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMitogen-activated protein kinase (MAPK) cascades play pivotal roles in mediating biotic and abiotic stress responses. In plants, MAPKs are classified into four major groups (A-D) according to their sequence homology and conserved phosphorylation motifs. Members of group A and B have been extensively characterized, but little information on the group D MAPKs has been reported.
resultsIn this study, we isolated and characterised GhMPK16, the first group D MAPK gene found in cotton. Southern blot analysis suggests GhMPK16 is single copy in the cotton genome, and RNA blot analysis indicates that GhMPK16 transcripts accumulate following pathogen infection and treatment with multiple defense-related signal molecules. The analysis of the promoter region of GhMPK16 revealed a group of putative cis-acting elements related to stress responses. Subcellular localization analysis suggests that GhMPK16 acts in the nucleus. Transgenic Arabidopsis overexpressing GhMPK16 displayed significant resistance to fungi (Colletotrichum nicotianae and Alternaria alternata) and bacteria (Pseudomonas solanacearum) pathogen, and the transcripts of pathogen-related (PR) genes were more rapidly and strongly induced in the transgenic plants. Furthermore, transgenic Arabidopsis showed reduced drought tolerance and rapid H2O2 accumulation.
conclusionThese results suggest that GhMPK16 might be involved in multiple signal transduction pathways, including biotic and abiotic stress signaling pathways.
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