Trial reportThe International journal of neuroscience2011
Reliability of peak treadmill exercise tests in mild Alzheimer disease.
Trial report in The International journal of neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Change in Fitness and the Relation to Change in Cognition and Neuropsychiatric Symptoms After Aerobic Exercise in Patients with Mild Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2018Trial
- A community-based approach to trials of aerobic exercise in aging and Alzheimer's disease.Contemporary clinical trials · 2012Trial
- Reference values for maximum oxygen consumption (VOBMJ open respiratory research · 2026Article
- Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord.Immunologic research · 2025Article
- Greater physical fitness (Acta physiologica (Oxford, England) · 2024Article
- Greater physical fitness (Vo2Max) in healthy older adults associated with increased integrity of the Locus Coeruleus-Noradrenergic system.Research square · 2023Article
- "Body & Brain": effects of a multicomponent exercise intervention on physical and cognitive function of adults with dementia - study protocol for a quasi-experimental controlled trial.BMC geriatrics · 2021Article
- Establishing Reference Cardiorespiratory Fitness Parameters in Alzheimer's Disease.Sports medicine international open · 2020Article
- Feasibility and Impact of a Multicomponent Exercise Intervention in Patients With Alzheimer's Disease: A Pilot Study.American journal of Alzheimer's disease and other dementias · 2019Article
- Determination of Aerobic Capacity via Cycle Ergometer Exercise Testing in Alzheimer's Disease.American journal of Alzheimer's disease and other dementias · 2017Article
- Cardiorespiratory fitness and white matter integrity in Alzheimer's disease.Brain imaging and behavior · 2016Article
- Validity of the step test for exercise prescription: no extension to a larger age range.Journal of aging and physical activity · 2013Article
- Alzheimer disease alters the relationship of cardiorespiratory fitness with brain activity during the stroop task.Physical therapy · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
introductionThe purpose of this study was to determine the reliability of treadmill peak exercise testing in people with very mild-to-mild Alzheimer disease (AD).
methodsSixteen subjects with very mild-to-mild AD performed graded peak treadmill exercise tests twice within a 14-day period. Heart rate, oxygen consumption, and respiratory exchange ratio (RER) were continuously monitored. Peak values were analyzed for absolute level of agreement.
resultsFourteen participants (87.5%) completed testing. Reliability was excellent with total peak oxygen consumption (VO2peak) (ml/kg/min) highly correlated across the two tests (r = 0.94, p < .001) with an intraclass correlation coefficient (ICC[3,1]) of 0.92 (95% confidence interval (CI) = 0.78, 0.97). The standard error of measurement (SEM) for VO2peak was 1.29 (95% CI = 0.88, 1.89).
conclusionsThese results indicate that peak exercise testing on a treadmill is reliable in the early stages of AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.