Evidence map›Paper›PMID 21574708›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2011

Lapse-induced surges in craving influence relapse in adult smokers: an experimental investigation.

William G Shadel, Steven C Martino, Claude Setodji, Daniel Cervone, Katie Witkiewitz, Ellen Burke Beckjord, Deborah Scharf, Regina Shih

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. A systematic review of the relationships between craving and smoking cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Pooled it
  2. Trial
  3. Trial
  4. An Automated, Online Feasibility Randomized Controlled Trial of a Just-In-Time Adaptive Intervention for Smoking Cessation (Quit Sense).Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Trial
  5. Trial
  6. Trial
  7. Trial
  8. Decline in cue-provoked craving during cue exposure therapy for smoking cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Trial
  9. Trial
  10. Trial
  11. Dependence and withdrawal-induced craving predict abstinence in an incentive-based model of smoking relapse.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  12. Trial
  13. Exploring the nature and relationship of tobacco cigarette craving and withdrawal.Journal of psychopathology and clinical science · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

William G ShadelRAND Corporation, Pittsburgh, Pennsylvania 15213, USA. shadel@rand.org
Steven C Martino
Claude Setodji
Daniel Cervone
Katie Witkiewitz
Ellen Burke Beckjord
Deborah Scharf
Regina Shih
RAND Corporation · USUniversity of Illinois Chicago · USWashington State University · US

Funding

Evaluating the Casual Pathways from Lapse to Relapse in SmokersR01CA127491 · NCI · RAND CORPORATION · PI SHADEL, WILLIAM G · 2008 to 2011
$2.3M
NCI NIH HHS R01 CA127491NCI NIH HHS R01CA127491
6 · The paper itself

Abstract

objectivesNearly all smokers who lapse experience a full-blown relapse, but the mediating mechanisms that contribute to this relationship are not well understood. A better understanding of these mechanisms would help to advance more effective relapse prevention treatments for smokers. The purpose of this study is to experimentally evaluate the effects of a programmed smoking lapse on smoking relapse and the effects of postlapse changes in craving on relapse.

methodAdult smokers (n = 63) who quit smoking with a brief cognitive-behavioral intervention and self-help materials were randomly assigned to one of two experimental conditions after 48 h of abstinence: No lapse (a no-smoking control/30-min waiting period) or lapse (smoking two cigarettes of their favored brand during a 30-min period). All participants were then followed daily for 14 days. Craving and biochemically verified self-reported abstinence were assessed on each follow-up day. Time (days) to relapse (7 consecutive days of smoking) was the main dependent measure.

resultsResults of Cox regression analysis revealed that participants in the lapse condition relapsed more quickly than participants in the no-lapse condition (hazard ratio [HR] = 2.12, 95% confidence interval [CI] = [1.03, 4.35]). These effects were attributable, in part, to episodic increases in craving among participants in the lapse condition only (HR = 12.42, 95% CI = [2.00, 77.1]).

conclusionsPreviously abstinent smokers who lapse are at risk for increased cigarette cravings and consequently, full-blown relapse. These results have implications for both cognitive-behavioral treatments for relapse prevention and for medications designed to help smokers manage cravings.

Indexed as

AdultBehavior TherapyFemaleHumansMaleMiddle AgedSecondary PreventionSmokingSmoking CessationSmoking Prevention

Identifiers

PMID21574708
PMCPMC3158283
OpenAlexW2019764813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.