ArticleBiomacromolecules2011
Inducing β-sheets formation in synthetic spider silk fibers by aqueous post-spin stretching.
Article in Biomacromolecules, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 72 citations in OpenAlex.
- Scale up of fermentation of recombinant Escherichia coli for efficient production of spider drag silk protein MaSp1s and its dimers.Microbial cell factories · 2025Article
- Charting the envelope of mechanical properties of synthetic silk fibers through predictive modeling of the drawing process.Science advances · 2025Article
- Post-spin Stretch Improves Mechanical Properties, Reduces Necking, and Reverts Effects of Aging in Biomimetic Artificial Spider Silk Fibers.ACS applied polymer materials · 2024Article
- A recombinant chimeric spider pyriform-aciniform silk with highly tunable mechanical performance.Materials today. Bio · 2024Article
- Replicating shear-mediated self-assembly of spider silk through microfluidics.Nature communications · 2024Article
- Spidroins under the Influence of Alcohol: Effect of Ethanol on Secondary Structure and Molecular Level Solvation of Silk-Like Proteins.Biomacromolecules · 2023Article
- An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates.Cell reports · 2023Article
- Spider Silk-Inspired Artificial Fibers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Interfacial Crystallization and Supramolecular Self-Assembly of Spider Silk Inspired Protein at the Water-Air Interface.Materials (Basel, Switzerland) · 2021Article
- Engineering Silk Materials: From Natural Spinning to Artificial Processing.Applied physics reviews · 2020Article
- Article
- Investigation of synthetic spider silk crystallinity and alignment via electrothermal, pyroelectric, literature XRD, and tensile techniques.Macromolecular materials and engineering · 2017Article
- The correlation between the length of repetitive domain and mechanical properties of the recombinant flagelliform spidroin.Biology open · 2017Article
- Evidence of Decoupling Protein Structure from Spidroin Expression in Spider Dragline Silks.International journal of molecular sciences · 2016Article
- Identification of Wet-Spinning and Post-Spin Stretching Methods Amenable to Recombinant Spider Aciniform Silk.Biomacromolecules · 2016Article
- Development of a Process for the Spinning of Synthetic Spider Silk.ACS biomaterials science & engineering · 2015Article
- Physical and biological regulation of neuron regenerative growth and network formation on recombinant dragline silks.Biomaterials · 2015Article
- Structure-function-property-design interplay in biopolymers: spider silk.Acta biomaterialia · 2014Review
- Effects of different post-spin stretching conditions on the mechanical properties of synthetic spider silk fibers.Journal of the mechanical behavior of biomedical materials · 2014Article
- Recombinant DNA production of spider silk proteins.Microbial biotechnology · 2013Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
As a promising biomaterial with numerous potential applications, various types of synthetic spider silk fibers have been produced and studied in an effort to produce man-made fibers with mechanical and physical properties comparable to those of native spider silk. In this study, two recombinant proteins based on Nephila clavipes Major ampullate Spidroin 1 (MaSp1) consensus repeat sequence were expressed and spun into fibers. Mechanical test results showed that fiber spun from the higher molecular weight protein had better overall mechanical properties (70 KD versus 46 KD), whereas postspin stretch treatment in water helped increase fiber tensile strength significantly. Carbon-13 solid-state NMR studies of those fibers further revealed that the postspin stretch in water promoted protein molecule rearrangement and the formation of β-sheets in the polyalanine region of the silk. The rearrangement correlated with improved fiber mechanical properties and indicated that postspin stretch is key to helping the spider silk proteins in the fiber form correct secondary structures, leading to better quality fibers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.