ArticleInternational journal of legal medicine2012
Good shedder or bad shedder--the influence of skin diseases on forensic DNA analysis from epithelial abrasions.
Article in International journal of legal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- "Shedding the status"-a meta-analysis on the individual propensity to shed skin material in the context of forensic trace analysis.International journal of legal medicine · 2025Pooled it
- Impact of fire extinguishing agents on DNA quantity and integrity.International journal of legal medicine · 2026Article
- Impact of face-derived DNA on touch DNA deposition on cell phone screens.International journal of legal medicine · 2026Article
- How to best assess shedder status: a comparison of popular shedder tests.International journal of legal medicine · 2025Article
- Article
- "I've never been at the crime scene!" - gloves as carriers for secondary DNA transfer.International journal of legal medicine · 2021Article
- The diversity of shedder tests and a novel factor that affects DNA transfer.International journal of legal medicine · 2021Review
- Persistence and detection of touch DNA and blood stain DNA on pig skin exposed to water.Forensic science, medicine, and pathology · 2020Article
- Cleaning a crime scene 2.0-what to do with the bloody knife after the crime?International journal of legal medicine · 2020Article
- Detection of cellular material in lip-prints.Forensic science, medicine, and pathology · 2019Article
- Laundry in a washing machine as a mediator of secondary and tertiary DNA transfer.International journal of legal medicine · 2018Article
- Impact of several wearers on the persistence of DNA on clothes-a study with experimental scenarios.International journal of legal medicine · 2018Article
- Persistence of DNA on clothes after exposure to water for different time periods-a study on bathtub, pond, and river.International journal of legal medicine · 2018Article
- Persistence of touch DNA on burglary-related tools.International journal of legal medicine · 2017Article
- Sex-specific age association with primary DNA transfer.International journal of legal medicine · 2016Article
- DNA transfer-a never ending story. A study on scenarios involving a second person as carrier.International journal of legal medicine · 2016Article
- Everything clean? Transfer of DNA traces between textiles in the washtub.International journal of legal medicine · 2015Article
- Influence of an individual's age on the amount and interpretability of DNA left on touched items.International journal of legal medicine · 2013Article
- Prediction of people's origin from degraded DNA--presentation of SNP assays and calculation of probability.International journal of legal medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The successful analysis of weak biological stains by means of highly sensitive short tandem repeat (STR) amplification has been increased significantly over the recent years. Nevertheless, the percentage of reliably analysable samples varies considerably between different crime scene investigations even if the nature of the stains appears to be the same. It has been proposed that the amount and quality of DNA left at a crime scene may be due to individual skin conditions (among other factors). Therefore, we investigated DNA from handprints from 30 patients acutely suffering from skin diseases like atopic dermatitis, psoriasis or skin ulcer before and after therapy by STR amplification using the new and highly sensitive Powerplex® ESX17 kit in comparison to 22 healthy controls. Handprints from atopic dermatitis patients showed a correct and reliable DNA profile in 90% and 40% of patients before and after therapy, respectively. Regarding psoriasis patients, we detected full DNA profiles in only 64% and 55% of handprints before and after therapy. In contrast, in ulcus patients and controls, full DNA profiles were obtained in much lower numbers. We conclude that active skin diseases like atopic dermatitis or psoriasis have a considerable impact on the amplificable DNA left by skin contact with surfaces. Since up to 7% of adults in European countries suffer from one of these diseases, this could explain at least partially the varying quality of DNA from weak stains.
Indexed as
Identifiers
21573897What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.