ArticlePloS one2011
A spatial analysis of county-level variation in syphilis and gonorrhea in Guangdong Province, China.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Epidemiological and Ecological Characterization of the EHEC O104:H4 Outbreak in Hamburg, Germany, 2011.PloS one · 2016Trial
- Spatiotemporal distribution of syphilis in Mainland China during the 17 years from 2004 to 2020.BMC public health · 2026Article
- Preconception syphilis seroprevalence and association with duration of marriage and age among married individuals in Guangdong Province, China: A population-based cross-sectional study.PLoS neglected tropical diseases · 2022Article
- Spatiotemporal distribution and sociodemographic and socioeconomic factors associated with primary and secondary syphilis in Guangdong, China, 2005-2017.PLoS neglected tropical diseases · 2021Article
- Spatiotemporal analysis of 11 years ofThe Lancet regional health. Western Pacific · 2021Article
- Exploring spatially varying demographic associations with gonorrhea incidence in Baltimore, Maryland, 2002-2005.Journal of geographical systems · 2020Article
- Association of Neighborhood Geographic Spatial Factors With Rates of Childhood Obesity.JAMA network open · 2018Article
- Landscape of emerging and re-emerging infectious diseases in China: impact of ecology, climate, and behavior.Frontiers of medicine · 2018Review
- The association between human perceived heat and early-stage syphilis and its variance: Results from a case-report system.The Science of the total environment · 2017Article
- Multivariate time series analysis on the dynamic relationship between Class B notifiable diseases and gross domestic product (GDP) in China.Scientific reports · 2016Article
- Social determinants of syphilis in South China: the effect of sibling position on syphilis and sexual risk behaviours.BMJ open · 2013Article
- The effect of a structural intervention for syphilis control among 3597 female sex workers: a demonstration study in South China.The Journal of infectious diseases · 2012Article
- Multilevel and spatial analysis of syphilis in Shenzhen, China, to inform spatially targeted control measures.Sexually transmitted infections · 2012Article
- A twin response to twin epidemics: integrated HIV/syphilis testing at STI clinics in South China.Journal of acquired immune deficiency syndromes (1999) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundSexually transmitted infections (STI) have made a resurgence in many rapidly developing regions of southern China, but there is little understanding of the social changes that contribute to this spatial distribution of STI. This study examines county-level socio-demographic characteristics associated with syphilis and gonorrhea in Guangdong Province. METHODS/PRINCIPAL
findingsThis study uses linear regression and spatial lag regression to determine county-level (n = 97) socio-demographic characteristics associated with a greater burden of syphilis, gonorrhea, and a combined syphilis/gonorrhea index. Data were obtained from the 2005 China Population Census and published public health data. A range of socio-demographic variables including gross domestic product, the Gender Empowerment Measure, standard of living, education level, migrant population and employment are examined. Reported syphilis and gonorrhea cases are disproportionately clustered in the Pearl River Delta, the central region of Guangdong Province. A higher fraction of employed men among the adult population, higher fraction of divorced men among the adult population, and higher standard of living (based on water availability and people per room) are significantly associated with higher STI cases across all three models. Gross domestic product and gender inequality measures are not significant predictors of reported STI in these models. CONCLUSIONS/SIGNIFICANCE: Although many ecological studies of STIs have found poverty to be associated with higher reported STI, this analysis found a greater number of reported syphilis cases in counties with a higher standard of living. Spatially targeted syphilis screening measures in regions with a higher standard of living may facilitate successful control efforts. This analysis also reinforces the importance of changing male sexual behaviors as part of a comprehensive response to syphilis control in China.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.