ReviewAfrican health sciences2011
Central nervous system tuberculosis.
Review in African health sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
76 citing papers in PubMed.
- Meningeal tuberculoma presenting as a space-occupying lesion in an immuno-competent young adult patient: A case report and literature review.Radiology case reports · 2026Article
- Concurrent pulmonary infection with Nocardia spp. and Mycobacterium tuberculosis in an adult with cerebral palsy: a case report.BMC infectious diseases · 2026Article
- Imaging manifestations of pediatric central nervous system tuberculosis in an endemic region.Radiology case reports · 2026Article
- When the Eye Reveals Disseminated Tuberculosis: A Pediatric Case of Endophthalmitis With Severe CNS Involvement.Case reports in ophthalmological medicine · 2026Article
- Central nervous system TB: a retrospective review of management.IJTLD open · 2025Article
- Tuberculous hemorrhagic meningoencephalitis. A rare manifestation of miliary TB. Case report and review.Radiology case reports · 2025Article
- A case report of long-segment tuberculous myelitis with concomitant tuberculous meningitis.AME case reports · 2025Article
- Ophthalmoplegia and vision loss in extrapulmonary tuberculosis with bilateral cavernous sinus involvement.IDCases · 2025Article
- Mycobacterium tuberculosis: The Mechanism of Pathogenicity, Immune Responses, and Diagnostic Challenges.Journal of clinical laboratory analysis · 2024Review
- Miliary meningeal tuberculosis - an unusual imaging presentation for an early definitive diagnosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Pontine tubercular abscess: A rare presentation of CNS tuberculosis masquerading as glioma in a child.Clinical case reports · 2024Article
- Assessment of Clinical, Histopathologic, and Radiologic Features in Extrapulmonary Tuberculosis Patients.Tanaffos · 2024Article
- Global research trends in central nervous system tuberculosis - A bibliometric analysis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024Review
- Central Nervous System Tuberculosis in a Murine Model: Neurotropic Strains or a New Pathway of Infection?Pathogens (Basel, Switzerland) · 2023Article
- Disseminated tuberculosis in an immunocompetent woman from the Himalayan region of Nepal: A case report.Clinical case reports · 2023Article
- Pediatric intracranial tuberculoma: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Association of blood neutrophil-lymphocyte ratio with short-term prognosis and severity of tuberculosis meningitis patients without HIV infection.BMC infectious diseases · 2023Article
- Stroke in a child with pulmonary tuberculosis and pleural effusion-An important clue for the diagnosis of disseminated central nervous system tuberculosis.Clinical case reports · 2023Article
- Central nervous system tuberculosis in immunocompetent patients: Two case reports with literature review.Radiology case reports · 2022Article
- Cerebral Tuberculoma with Mild Posterior Cervical Pain as the Main Symptom Despite Extensive Brain Lesions.Internal medicine (Tokyo, Japan) · 2022Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central nervous system (CNS) involvement, one of the most devastating clinical manifestations of tuberculosis (TB) is noted in 5 to 10% of extrapulmonary TB cases, and accounts for approximately 1% of all TB cases. Definitive diagnosis of tuberculous meningitis (TBM) depends upon the detection of the tubercle bacilli in the CSF. Every patient with TBM should preferably be evaluated by imaging with contrast enhanced CT either before or within the first 48 hours of treatment. An extra-neural focus of tuberculosis should be sought clinically and radiologically in all patients with CNS TB as it may indicate safer and more accessible sites for diagnostic samplings. A minimum of 10 months treatment is warranted, prompted by the uncertain influences of disease severity, CNS drug penetration, undetected drug resistance and patient compliance. All patients with TB meningitis may receive adjunctive corticosteroids at presentation regardless of disease severity even for those with HIV infection. Drug resistance is strongly associated with previous treatment. The key principle of managing drug-resistant TB is never to add a single drug to a failing regimen. Early ventriculo-peritoneal shunting should be considered in those with hydrocephalus failing medical management. The single most important determinant of outcome is the stage of tuberculous meningitis at which treatment has been started.
Indexed as
Identifiers
21572867PMC3092316What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.