ArticleAsian journal of transfusion science2011
Prevalence and specificities of red cell alloantibodies among blood recipients in the Malaysian state of Kelantan.
Article in Asian journal of transfusion science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Global Prevalence and Specificity of Red Blood Cell Antibodies in Blood Donors: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2026Review
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- Prevalence of Red Blood Cell Alloimmunization among Transfused Chronic Kidney Disease Patients in Hospital Universiti Sains Malaysia.Oman medical journal · 2020Article
- Kidd Blood Group Genotyping for Thalassemia Patient in Iran.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020Article
- Red blood cell alloimmunization in multi-transfused patients with chronic kidney disease in Port Harcourt, South-South Nigeria.African health sciences · 2018Article
- Erythrocyte Alloimmunization and Autoimmunization among Blood Donors and Recipients visiting a Tertiary Care Hospital.Journal of clinical and diagnostic research : JCDR · 2017Article
- Presence of Irregular Antibody (Anti-c) in a Multitransfused Cardiac Surgery Patient.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2015Article
- Prevalence and specificities of red cell alloantibodies in transfusion-dependent beta thalassemia patients in Yazd.Iranian journal of pediatric hematology and oncology · 2015Article
- Frequency and specificity of red blood cell alloimmunization in chilean transfused patients.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2015Article
- Hemolytic disease of fetus and newborn due to maternal red blood cell alloantibodies in the Malay population.Asian journal of transfusion science · 2014Article
- Clinical significance of antibody specificities to M, N and Lewis blood group system.Asian journal of transfusion science · 2014Article
- Prevalence and Specificity of RBC Alloantibodies in Indian Patients Attending a Tertiary Care Hospital.Advances in hematology · 2014Article
- Hemolytic disease of the fetus and newborn caused by anti-E.Asian journal of transfusion science · 2013Article
- Red cell phenotyping of blood from donors at the National blood center of Malaysia.Asian journal of transfusion science · 2012Article
- Red blood cell alloimmunization among transfusion-dependent thalassemia major patients in Northeastern Iran.Asian journal of transfusion scienceArticle
- Red cell alloimmunization in multitransfused hepatobiliary patients at hospital Selayang.Asian journal of transfusion scienceArticle
- Red blood cell alloimmunization among rhesus D-negative patients in a teaching hospital in Northeastern Malaysia.Asian journal of transfusion scienceArticle
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5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRed blood cell (RBC) alloantibodies may be formed following exposure to RBC antigens. In most cases, the alloimmunization develops during pregnancy or from previous blood transfusions. The RBC antigens and their alloantibodies vary among different human populations and ethnic groups, and they do have a clinical significance for their adverse immunological reactions.
aimsThis study aimed at studying the prevalence of RBC alloantibodies at the Blood Transfusion Unit of Hospital Raja Perempuan Zainab II in Kota Bharu, Malaysia. PATIENTS AND
methodsA cross-sectional study was performed utilizing data obtained in the years 2007 and 2008. Data of antibody screening tests from 5719 patients were examined. RESULTS AND DISCUSSION: The overall prevalence of alloimmunization was 65 (1.13%). The majority of these had a single alloantibody (76.9%), whereas the remaining 23.1% had multiple antibodies. The anti-E antibody comprised the most common alloantibody (24.6%) followed by the anti-Lewis (a) antibodies (18.5%) and the anti-M antibody (13.8%). There were more female recipients than males.
conclusionsIt was concluded that the findings of this work have been comparable with other published works, and that the main factors associated with alloantibody formation were multiple transfusions and pregnancies. The study also emphasizes the necessity for carrying out immunohematology studies prior to every blood transfusion especially in cases that require multiple transfusions for a long period of time such as in thalassemia patients.
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