Evidence map›Paper›PMID 21572557›Full record

ArticleComputers & structures2011

Quantifying blood flow and wall shear stresses in the outflow tract of chick embryonic hearts.

Aiping Liu, Andrew Nickerson, Aaron Troyer, Xin Yin, Robert Cary, Kent Thornburg, Ruikang Wang, Sandra Rugonyi

Abstract read
In one paragraph

Article in Computers & structures, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Removing vessel constriction on the embryonic heart results in changes in valve gene expression, morphology, and hemodynamics.Developmental dynamics : an official publication of the American Association of Anatomists · 2018
    Article
  8. Article
  9. Article
  10. Placental Origins of Chronic Disease.Physiological reviews · 2016
    Review
  11. Article
  12. Review
  13. Effect of Outflow Tract Banding on Embryonic Cardiac Hemodynamics.Journal of cardiovascular development and disease · 2016
    Article
  14. Article
  15. Article
  16. Left atrial ligation alters intracardiac flow patterns and the biomechanical landscape in the chick embryo.Developmental dynamics : an official publication of the American Association of Anatomists · 2014
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aiping LiuDivision of Biomedical Engineering, Oregon Health & Science University, Portland, OR, 97239, USA.
Andrew Nickerson
Aaron Troyer
Xin Yin
Robert Cary
Kent Thornburg
Ruikang Wang
Sandra Rugonyi
Oregon Health & Science University · US

Funding

Dynamic changes in the chick developing heart in response to altered hemodynamicsR01HL094570 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI RUGONYI, SANDRA · 2009 to 2017
$3.8M
NHLBI NIH HHS R01 HL094570
6 · The paper itself

Abstract

Wall shear stresses (WSS) exerted by blood flow on cardiac tissues modulate growth and development of the heart. To study the role of hemodynamic conditions on cardiac morphogenesis, here, we present a methodology that combines imaging and finite element modeling to quantify the in vivo blood flow dynamics and WSS in the cardiac outflow tract (OFT) of early chicken embryos (day 3 out of 21-day incubation period). We found a distinct blood flow field and heterogeneous distribution of WSS in the chicken embryonic heart OFT, which have physiological implications for OFT morphogenesis.

Identifiers

PMID21572557
PMCPMC3091009
OpenAlexW1966891540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.