ReviewCurrent opinion in pediatrics2011
Recent progress in understanding pediatric pulmonary hypertension.
Review in Current opinion in pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 53 citations in OpenAlex.
- SurgicalThe open respiratory medicine journal · 2020Article
- Risk Factors for Obstructive Sleep Apnea Syndrome in Children: State of the Art.International journal of environmental research and public health · 2019Review
- Prevalence of Pulmonary Hypertension in Pediatric Patients With Obstructive Sleep Apnea and a Cardiology Evaluation: A Retrospective Analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Surgery for partial atrioventricular septal defect with pulmonary hypertension in an adult dog.The Journal of veterinary medical science · 2018Article
- Trends in pediatric pulmonary hypertension-related hospitalizations in the United States from 2000-2009.Pulmonary circulation · 2015Article
- Pulmonary arterial hypertension associated with congenital heart disease and Eisenmenger syndrome: current practice in pediatrics.Minerva pediatrica · 2015Review
- Serum Pentraxin 3 and hs-CRP Levels in Children with Severe Pulmonary Hypertension.Balkan medical journal · 2014Article
- Biomarkers for pediatric pulmonary arterial hypertension - a call to collaborate.Frontiers in pediatrics · 2014Review
- Diagnosis and treatment of pulmonary hypertension in infancy.Early human development · 2013Article
- Obstructive sleep apnea in children: a critical update.Nature and science of sleep · 2013Review
- Pulmonary hypertension in bronchopulmonary dysplasia.Seminars in perinatology · 2013Review
- Frontiers in pulmonary hypertension in infants and children with bronchopulmonary dysplasia.Pediatric pulmonology · 2012Review
- Pharmacotherapy for pulmonary hypertension.Pediatric clinics of North America · 2012Review
- Clinical pharmacological studies in children: From exploratory towards confirmation driven methodology.World journal of clinical pediatrics · 2012Article
- Plasma proteomics of differential outcome to long-term therapy in children with idiopathic pulmonary arterial hypertension.Proteomics. Clinical applications · 2012Article
- Advances in pediatric pulmonary arterial hypertension.Current opinion in cardiology · 2012Review
- Circulating cytokines and growth factors in pediatric pulmonary hypertension.Mediators of inflammation · 2012Article
- A Retrospective Review of Infants Receiving Sildenafil.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewPulmonary artery hypertension (PAH) in children contributes significantly to morbidity and mortality in diverse pediatric cardiac, lung, hematologic and other diseases. Advances in pulmonary vascular biology over the past few decades have significantly expanded therapeutic strategies; however, many unique issues persist regarding our understanding of pediatric PAH. RECENT
findingsRecent studies of pediatric PAH include those that highlight gaps in our understanding of pediatric diseases associated with PAH from those of adult onset, emphasizing the strong need for specific studies regarding unique aspects of the pathogenesis and treatment of children with PAH. Registries have begun to provide new data showing differences in physiology, course, and genetics between adult and pediatric forms of PAH. Unfortunately, therapeutic strategies in pediatric pulmonary hypertension are often limited to small observational studies in children and are dependent on results from larger adult studies. In addition, clinical endpoints for studies and care remain poorly defined in infants and children. SUMMARY: Despite many advances, long-term outcomes for children with PAH remain guarded and substantial challenges persist, especially with regard to understanding mechanisms and approach to severe PAH. Future studies are needed to develop novel biomarkers, clinical endpoints and interventions for young children with diverse causes of PAH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.