ReviewAmerican journal of physiology. Heart and circulatory physiology2011
Doppler velocity measurements from large and small arteries of mice.
Review in American journal of physiology. Heart and circulatory physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 55 citations in OpenAlex.
- Article
- Non-invasive real-time pulsed Doppler assessment of blood flow in mouse ophthalmic artery.Cell reports methods · 2025Article
- Mouse Cardiovascular Imaging.Current protocols · 2024Review
- Phosphodiesterases Mediate the Augmentation of Myogenic Constriction by Inhibitory G Protein Signaling and is Negatively Modulated by the Dual Action of RGS2 and 5.Function (Oxford, England) · 2024Article
- Modification of Peripheral Blood Flow and Angiogenesis by COBiomedicines · 2023Article
- Comparison and optimization of pCASL and VSASL for rat thoracolumbar spinal cord MRI at 9.4 T.Magnetic resonance in medicine · 2023Article
- Multi-omic analysis of the cardiac cellulome defines a vascular contribution to cardiac diastolic dysfunction in obese female mice.Basic research in cardiology · 2023Article
- Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs.Journal of visualized experiments : JoVE · 2022Article
- MRI-based in vivo detection of coronary microvascular dysfunction before alterations in cardiac function induced by short-term high-fat diet in mice.Scientific reports · 2021Article
- The Progress of Advanced Ultrasonography in Assessing Aortic Stiffness and the Application Discrepancy between Humans and Rodents.Diagnostics (Basel, Switzerland) · 2021Review
- A surgical mouse model of neonatal pressure overload by transverse aortic constriction.Nature protocols · 2021Article
- TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.EMBO molecular medicine · 2019Article
- Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation.JCI insight · 2019Article
- In Vivo Flow Cytometry of Extremely Rare Circulating Cells.Scientific reports · 2019Article
- Sex-dependent differences in central artery haemodynamics in normal and fibulin-5 deficient mice: implications for ageing.Proceedings. Mathematical, physical, and engineering sciences · 2019Article
- Coronary Microvascular Remodeling in Type 2 Diabetes: Synonymous With Early Aging?Frontiers in physiology · 2018Article
- Absence of Endothelial ERα Results in Arterial Remodeling and Decreased Stiffness in Western Diet-Fed Male Mice.Endocrinology · 2017Article
- Ultrasound detection of altered placental vascular morphology based on hemodynamic pulse wave reflection.American journal of physiology. Heart and circulatory physiology · 2017Article
- Endothelial Estrogen Receptor-α Does Not Protect Against Vascular Stiffness Induced by Western Diet in Female Mice.Endocrinology · 2016Article
- Cardiovascular Imaging in Mice.Current protocols in mouse biology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
With the growth of genetic engineering, mice have become increasingly common as models of human diseases, and this has stimulated the development of techniques to assess the murine cardiovascular system. Our group has developed nonimaging and dedicated Doppler techniques for measuring blood velocity in the large and small peripheral arteries of anesthetized mice. We translated technology originally designed for human vessels for use in smaller mouse vessels at higher heart rates by using higher ultrasonic frequencies, smaller transducers, and higher-speed signal processing. With these methods one can measure cardiac filling and ejection velocities, velocity pulse arrival times for determining pulse wave velocity, peripheral blood velocity and vessel wall motion waveforms, jet velocities for the calculation of the pressure drop across stenoses, and left main coronary velocity for the estimation of coronary flow reserve. These noninvasive methods are convenient and easy to apply, but care must be taken in interpreting measurements due to Doppler sample volume size and angle of incidence. Doppler methods have been used to characterize and evaluate numerous cardiovascular phenotypes in mice and have been particularly useful in evaluating the cardiac and vascular remodeling that occur following transverse aortic constriction. Although duplex ultrasonic echo-Doppler instruments are being applied to mice, dedicated Doppler systems are more suitable for some applications. The magnitudes and waveforms of blood velocities from both cardiac and peripheral sites are similar in mice and humans, such that much of what is learned using Doppler technology in mice may be translated back to humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.