ArticleJournal of pain and symptom management2011
Cancer-related pain and disability: a longitudinal study.
Article in Journal of pain and symptom management, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Chronic pain and comorbid mental health conditions: independent associations of posttraumatic stress disorder and depression with pain, disability, and quality of life.Journal of behavioral medicine · 2015Trial
- Determinants of pain severity changes in ambulatory patients with cancer: an analysis from Eastern Cooperative Oncology Group trial E2Z02.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Trial
- Somatic symptoms in cancer patients trajectory over 12 months and impact on functional status and disability.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Trial
- Patient Health Questionnaire Anxiety and Depression Scale: Initial Validation in Three Clinical Trials.Psychosomatic medicineTrial
- Predictors of cancer-related pain improvement over time.Psychosomatic medicineTrial
- Investigation of an integrated standardised pain assessment and management tool in addition to usual care versus usual care alone in oncology outpatient clinics for adults with pain: the CAPTURE cluster randomised pilot trial protocol. ISRCRN86926298.Pilot and feasibility studies · 2025Article
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- A Guide to Inpatient Cancer Rehabilitation: Focusing on Patient Selection and Evidence-Based Outcomes.PM & R : the journal of injury, function, and rehabilitation · 2017Review
- The relationship between pain management and psychospiritual distress in patients with advanced cancer following admission to a palliative care unit.BMC palliative care · 2015Article
- Development of the Global Disability Scale (Glo.Di.S): preliminary results.Annals of general psychiatry · 2012Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
contextAlthough the cross-sectional association between cancer-related pain and disability is well established, their longitudinal relationship has been less studied.
objectivesData from the Indiana Cancer Pain and Depression (INCPAD) trial were analyzed to determine whether baseline cancer-related pain and changes in pain over time predict disability over 12 months.
methodsA total of 274 cancer survivors with cancer-related pain were accrued in the INCPAD trial. Data were collected at baseline, one, three, six, and 12 months by interviewers blinded to treatment arm. Disability outcomes included a continuous measure (Sheehan Disability Scale [SDS] score) and a categorical measure (≥14 days in the past four weeks with a ≥50% reduction in usual activities). Predictor variables, operationalized by the Brief Pain Inventory, included baseline pain severity and changes in pain severity scores between each time point. Multivariable analyses were conducted adjusting for treatment group, baseline disability, and selected covariates including depression.
resultsBaseline pain severity did not predict disability outcomes at 12 months. However, improvement in pain severity predicted less disability over 12 months both in terms of SDS scores (b=-0.17, t=-5.33, P<0.001) and ≥14 disability days in the past month (odds ratio=0.85; 95% confidence interval, 0.79-0.93; P<0.001).
conclusionDisability over 12 months in patients with cancer-related pain is predicted by changes in pain severity over time. Results suggest that effective pain management may reduce subsequent disability among cancer survivors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.