ArticleLipids in health and disease2011
Exercise and spirulina control non-alcoholic hepatic steatosis and lipid profile in diabetic Wistar rats.
Article in Lipids in health and disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02837666 (Independent and Synergistic Effect of Spirulina Maxima With Exercise on General Fitness, Lipid Profile and Antioxidant Capacity in Overweight and Obese Subjects), which is not on this map. Cited by 21 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Independent and Synergistic Effect of Spirulina Maxima With Exercise on General Fitness, Lipid Profile and Antioxidant Capacity in Overweight and Obese Subjects
Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Hypolipidemic Effect ofMarine drugs · 2019Trial
- Double-blind randomised controlled trial of the independent and synergistic effect ofBMJ open · 2017Trial
- Impact of daily supplementation of Spirulina platensis on the immune system of naïve HIV-1 patients in Cameroon: a 12-months single blind, randomized, multicenter trial.Nutrition journal · 2015Trial
- Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study.Lipids in health and disease · 2014Trial
- The effect ofFood science & nutrition · 2022Article
- Blood lipid profile changes in type 2 diabetic rats after tail suspension and reloading.Lipids in health and disease · 2021Article
- Effect of spirulina and chlorella alone and combined on the healing process of diabetic wounds: an experimental model of diabetic rats.Journal of diabetes and metabolic disorders · 2021Article
- Impact ofInternational journal of environmental research and public health · 2021Article
- The effects of spirulina under high-intensity interval training on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females: A randomized, controlled, single-blind trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Spirulina Enhances Bone Modeling in Growing Male Rats by Regulating Growth-Related Hormones.Nutrients · 2020Article
- Systematic Physical Exercise andAntioxidants (Basel, Switzerland) · 2019Article
- Monocyte chemoattractant protein-1 polymorphism interaction with spirulina immunomodulatory effects in healthy Korean elderly: A 16 week, double-blind randomized clinical trial.Nutrition research and practice · 2017Article
- Article
- Selective protein depletion impairs bone growth and causes liver fatty infiltration in female rats: prevention by Spirulina alga.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- The influence of obesity on the effects of spirulina supplementation in the human metabolic response of Korean elderly.Nutrition research and practice · 2016Article
- Effects of physical activity upon the liver.European journal of applied physiology · 2015Review
- Short term resistance training enhanced plasma apoA-I and FABP4 levels in Streptozotocin-induced diabetic rats.Journal of diabetes and metabolic disorders · 2014Article
- Health benefits of blue-green algae: prevention of cardiovascular disease and nonalcoholic fatty liver disease.Journal of medicinal food · 2013Review
- Effects of physical training with different intensities of effort on lipid metabolism in rats submitted to the neonatal application of alloxan.Lipids in health and disease · 2012Article
- The role of bilirubin in diabetes, metabolic syndrome, and cardiovascular diseases.Frontiers in pharmacology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus is associated with metabolic dysfunctions, including alterations in circulating lipid levels and fat tissue accumulation, which causes, among other pathologies, non-alcoholic fatty liver disease (NAFLD). AIM OF THE STUDY: The objective of this study was to analyse the effects of physical exercise and spirulina intake on the control of NAFLD in diabetic Wistar rats.
methodsDiabetes was induced in the animals through intravenous administration of alloxan. The rats were divided into four groups: Diabetic Control (DC) - diabetic rats fed with a control diet and no physical exercise; Diabetic Spirulina (DS) - diabetic rats fed with a diet that included spirulina; Diabetic Spirulina and Exercise (DSE) - diabetic rats fed with a diet that included Spirulina and that exercised; and Diabetic Exercise (DE) - diabetic rats fed with a control diet and that exercised.
resultsThe groups DS, DSE, and DE presented lower plasma concentrations of LDL cholesterol than DC, as well as lower levels of total liver lipids in groups DS, DSE, and DE in comparison to DC.
conclusionThus, spirulina appears to be effective in reducing total circulating levels of LDL-cholesterol and hepatic lipids, alone or in conjunction with physical exercise in diabetic rats.
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