ArticleJournal of cognitive neuroscience2011
Updating existing emotional memories involves the frontopolar/orbito-frontal cortex in ways that acquiring new emotional memories does not.
Article in Journal of cognitive neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Unlocking the neural mechanisms of consumer loan evaluations: an fNIRS and ML-based consumer neuroscience study.Frontiers in human neuroscience · 2024Article
- Food stimuli decrease activation in regions of the prefrontal cortex related to executive function: an fNIRS study.Eating and weight disorders : EWD · 2023Article
- Negative emotional content disrupts the coherence of episodic memories.Journal of experimental psychology. General · 2018Article
- Brain substrates of recovery from misleading influence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Association learning for emotional harbinger cues: when do previous emotional associations impair and when do they facilitate subsequent learning of new associations?Emotion (Washington, D.C.) · 2014Article
- Not all that glittered is gold: neural mechanisms that determine when reward will enhance or impair memory.Frontiers in neuroscience · 2014Article
- Current research and emerging directions in emotion-cognition interactions.Frontiers in integrative neuroscience · 2014Article
- Attenuating age-related learning deficits: emotional valenced feedback interacts with task complexity.Emotion (Washington, D.C.) · 2013Article
- Both younger and older adults have difficulty updating emotional memories.The journals of gerontology. Series B, Psychological sciences and social sciences · 2013Article
- The long rather than the short allele of 5-HTTLPR predisposes Han Chinese to anxiety and reduced connectivity between prefrontal cortex and amygdala.Neuroscience bulletin · 2013Article
- Age-related similarities and differences in brain activity underlying reversal learning.Frontiers in integrative neuroscience · 2013Article
- Differential brain activity during emotional versus nonemotional reversal learning.Journal of cognitive neuroscience · 2012Article
- Threat of punishment motivates memory encoding via amygdala, not midbrain, interactions with the medial temporal lobe.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- High reward makes items easier to remember, but harder to bind to a new temporal context.Frontiers in integrative neuroscience · 2012Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
In life, we must often learn new associations to people, places, or things we already know. The current fMRI study investigated the neural mechanisms underlying emotional memory updating. Nineteen participants first viewed negative and neutral pictures and learned associations between those pictures and other neutral stimuli, such as neutral objects and encoding tasks. This initial learning phase was followed by a memory updating phase, during which participants learned picture-location associations for old pictures (i.e., pictures previously associated with other neutral stimuli) and new pictures (i.e., pictures not seen in the first phase). There was greater frontopolar/orbito-frontal (OFC) activity when people learned picture-location associations for old negative pictures than for new negative pictures, but frontopolar OFC activity did not significantly differ during learning locations of old versus new neutral pictures. In addition, frontopolar activity was more negatively correlated with the amygdala when participants learned picture-location associations for old negative pictures than for new negative or old neutral pictures. Past studies revealed that the frontopolar OFC allows for updating the affective values of stimuli in reversal learning or extinction of conditioning [e.g., Izquierdo, A., & Murray, E. A. Opposing effects of amygdala and orbital PFC lesions on the extinction of instrumental responding in macaque monkeys. European Journal of Neuroscience, 22, 2341-2346, 2005]; our findings suggest that it plays a more general role in updating associations to emotional stimuli.
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