Evidence map›Paper›PMID 21567461›Full record

ArticleJournal of clinical laboratory analysis2011

Prevalence of IgA antitissue transglutaminase antibodies in children with type 1 diabetes mellitus.

Samaşca Gabriel, Iancu Mihaela, Butnariu Angela, Andreica Mariana, Dejica Doru

Abstract read
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Article in Journal of clinical laboratory analysis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Helicobacter pylori prevalence and risk factors among children with celiac disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Article
  2. Article
  3. Article
  4. Coexistence of coeliac disease and type 1 diabetes.Przeglad gastroenterologiczny · 2014
    Review
  5. Article
  6. Celiac disease in type 1 diabetes mellitus.Italian journal of pediatrics · 2012
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samaşca GabrielDepartment of Immunopathology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Gabriel.Samasca@umfcluj.ro
Iancu Mihaela
Butnariu Angela
Andreica Mariana
Dejica Doru

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThe association of celiac disease with type 1 diabetes mellitus is known, but the evolution of celiac disease is most frequently asymptomatic, without any clinical signs. Thus, diagnosis is impossible to make in the absence of serological tests. Our study aimed to determine the prevalence and the efficiency of IgA antitissue transglutaminase antibodies in the screening of celiac disease in children with type 1 diabetes mellitus.

methodDuring the course of 2008-2009, we performed an analytical clinical study that included the determination of IgA antitissue transglutaminase antibodies in a group of 119 children with type 1 diabetes mellitus. Fifty-seven percent of the subjects were male and 43% were female, with a mean age of 11±4 years.

resultsBy evaluating IgA antitissue transglutaminase antibodies, we obtained a prevalence of 9.2% in children with type 1 diabetes mellitus, with a sensitivity and specificity of 80 and 82.6%, respectively.

conclusionsThere is an increased prevalence of IgA antitissue transglutaminase antibodies, which suggests the need to use this method as an effective first-line test in the screening of celiac disease in children with type 1 diabetes mellitus.

Indexed as

ChildDiabetes Mellitus, Type 1FemaleGeographyGlycated HemoglobinGTP-Binding ProteinsHumansImmunoenzyme TechniquesImmunoglobulin AImmunoglobulin GMalePrevalenceProtein Glutamine gamma Glutamyltransferase 2Reference StandardsTransglutaminasesGlycated HemoglobinGTP-Binding Proteinshemoglobin A1c protein, humanImmunoglobulin AImmunoglobulin GProtein Glutamine gamma Glutamyltransferase 2Transglutaminases

Identifiers

PMID21567461
PMCPMC6647590

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.