Evidence map›Paper›PMID 21567259›Full record

Trial reportInternational urogynecology journal2011

Weight loss improves fecal incontinence severity in overweight and obese women with urinary incontinence.

Alayne D Markland, Holly E Richter, Kathryn L Burgio, Deborah L Myers, Alexandra L Hernandez, Leslee L Subak

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International urogynecology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Faecal incontinence in adults.Nature reviews. Disease primers · 2022
    Review
  7. Personality of patients with fecal incontinence.International journal of colorectal disease · 2021
    Observational
  8. Article
  9. Evidence-Based Update on Treatments of Fecal Incontinence in Women.Obstetrics and gynecology clinics of North America · 2016
    Review
  10. The Epidemiology of Pelvic Floor Disorders and Childbirth: An Update.Obstetrics and gynecology clinics of North America · 2016
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Conservative treatment for anal incontinence.Gastroenterology report · 2014
    Article
  17. Review
  18. Article
  19. Article
  20. Risk factors for fecal incontinence in older women.The American journal of gastroenterology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alayne D MarklandGeriatric Research, Education, and Clinical Center, Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, BVAMC, GRECC 11-G, Room 8220, 700 South 19th Street, Birmingham, AL 35233, USA. amarkland@aging.uab.edu
Holly E Richter
Kathryn L Burgio
Deborah L Myers
Alexandra L Hernandez
Leslee L Subak
University of Alabama at Birmingham · USUniversity of California, San Francisco · USBrown University · USGeriatric Research Education and Clinical Center · US

Funding

Weight Reduction for Incontinence Network(WIN)U01DK067860 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRADY, DEBORAH G · 2003 to 2007
$2.3M
Weight Reduction for Incontinence NetworkU01DK067861 · NIDDK · MIRIAM HOSPITAL · PI WING, RENA R · 2003 to 2007
$2.2M
Weight Reduction for Incontinence Network (WIN)U01DK067862 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FRANKLIN, FRANK A · 2003 to 2007
$1.7M
Patient Oriented Research and Mentoring in Obesity and Urinary IncontinenceK24DK080775 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SUBAK, LESLEE L · 2008 to 2019
$1.7M
NIDDK NIH HHS K24 DK080775NIDDK NIH HHS U01 DK067860NIDDK NIH HHS U01DK067860NIDDK NIH HHS U01 DK067861NIDDK NIH HHS U01 DK067862
6 · The paper itself

Abstract

introduction/hypothesisTo estimate the effect of weight loss on fecal incontinence (FI) severity among overweight and obese women with urinary incontinence, we analyzed data from women randomized to a weight loss intervention or control condition.

methodsThe modified Fecal Incontinence Severity Index (FISI) was administered at 6, 12, and 18 months in 338 women. Repeated measures analyses identified factors associated with improved FISI scores among women with baseline scores >0.

resultsFISI scores improved in 45 (13%) across all time points among the 291 women (87%) completing the trial. Improved scores were associated with a one-point lower urinary tract symptoms (LUTS) score, p < 0.01. Improved liquid stool FI frequency was associated with ≥ 5 kg weight loss (p = 0.001), 10-g increase in fiber intake (p = 0.05), and decreased LUTS (p = 0.003).

conclusionsFI severity improved with weight loss. Women with liquid stool FI losing at least 5 kg and/or increased dietary fiber intake had improved FI frequency.

Indexed as

Severity of Illness IndexWeight LossAdultBody Mass IndexFecal IncontinenceFemaleHumansLongitudinal StudiesMiddle AgedObesitySurveys and QuestionnairesUrinary Incontinence

Identifiers

PMID21567259
PMCPMC3204612
OpenAlexW2035760779

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.