ReviewChromosoma2011
The torsional state of DNA within the chromosome.
Review in Chromosoma, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- The Roles of Topoisomerases in Transcriptional Regulation.International journal of molecular sciences · 2026Review
- Gel Electrophoresis Analysis of SMC-Mediated Effects on DNA Topology.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Electrophoretic Analysis of DNA Supercoiling Activities.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Nucleosomal DNA has topological memory.Nature communications · 2024Article
- Force spectroscopy with electromagnetic tweezers.Journal of applied physics · 2021Article
- DNA-Topology Simplification by Topoisomerases.Molecules (Basel, Switzerland) · 2021Review
- DNA Manipulation and Single-Molecule Imaging.Molecules (Basel, Switzerland) · 2021Review
- Emerging roles for R-loop structures in the management of topological stress.The Journal of biological chemistry · 2020Review
- Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA.Nucleic acids research · 2019Article
- Structure and Chromosomal Organization of Yeast Genes Regulated by Topoisomerase II.International journal of molecular sciences · 2018Review
- Probing the salt dependence of the torsional stiffness of DNA by multiplexed magnetic torque tweezers.Nucleic acids research · 2017Article
- Controlling gene expression by DNA mechanics: emerging insights and challenges.Biophysical reviews · 2016Review
- Controlling gene expression by DNA mechanics: emerging insights and challenges.Biophysical reviews · 2016Review
- Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils.The EMBO journal · 2014Article
- Topoisomerase II regulates yeast genes with singular chromatin architectures.Nucleic acids research · 2013Article
- Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα.The Journal of biological chemistry · 2013Article
- Transcription-dependent dynamic supercoiling is a short-range genomic force.Nature structural & molecular biology · 2013Article
- Torque measurement at the single-molecule level.Annual review of biophysics · 2013Review
- Topoisomerase II is required for the production of long Pol II gene transcripts in yeast.Nucleic acids research · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Virtually all processes of the genome biology affect or are affected by the torsional state of DNA. Torsional energy associated with an altered twist facilitates or hinders the melting of the double helix, its molecular interactions, and its spatial folding in the form of supercoils. Yet, understanding how the torsional state of DNA is modulated remains a challenging task due to the multiplicity of cellular factors involved in the generation, transmission, and dissipation of DNA twisting forces. Here, an overview of the implication of DNA topoisomerases, DNA revolving motors, and other DNA interactions that determine local levels of torsional stress in bacterial and eukaryotic chromosomes is provided. Particular emphasis is made on the experimental approaches being developed to assess the torsional state of intracellular DNA and its organization into topological domains.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.