Evidence map›Paper›PMID 21566698›Full record

ArticlePhosphorus, sulfur, and silicon and the related elements2011

Approaches to tyrosine-linked peptidomimetic prodrugs of (S)-HPMP-based acyclic nucleoside phosphonates.

Valeria M Zakharova, Ivan S Krylov, Michaela Serpi, Boris A Kashemirov, Charles E McKenna

Abstract read
In one paragraph

Article in Phosphorus, sulfur, and silicon and the related elements, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valeria M ZakharovaDepartment of Chemistry, University of Southern California, Los Angeles, CA 90089-0744, USA.
Ivan S Krylov
Michaela Serpi
Boris A Kashemirov
Charles E McKenna

Funding

Oral Antiviral Prodrugs for Biodefense InitiativeU01AI061457 · NIAID · TSRL, INC. · PI HILFINGER, JOHN M · 2005 to 2009
$5.3M
Improving Absorption and Targeting of Antiviral DrugsR44AI056864 · NIAID · TSRL, INC. · PI HILFINGER, JOHN M · 2007 to 2009
$3.0M
Improving Absorption and Targeting of Antiviral DrugsR43AI056864 · NIAID · TSRL, INC. · PI HILFINGER, JOHN M · 2003 to 2004
$927k
NIAID NIH HHS R43 AI056864NIAID NIH HHS R44 AI056864NIAID NIH HHS U01 AI061457
6 · The paper itself

Abstract

Synthetic approaches to a new class of tyrosine-linked prodrugs of two 3-hydroxy-2-(phosphonomethoxypropyl) (HPMP) nucleotide analogues ((S)-HPMPC and (S)-HPMPA) are outlined.

Identifiers

PMID21566698
PMCPMC3090212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.