ReviewJournal of applied physiology (Bethesda, Md. : 1985)2011
Effects of exercise training on coronary collateralization and control of collateral resistance.
Review in Journal of applied physiology (Bethesda, Md. : 1985), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Effects of moderate physical training program in post-myocardial infarction patients with arterial hypertension.European journal of translational myology · 2025Article
- HBasic research in cardiology · 2025Article
- Experimental and theoretical model of microvascular network remodeling and blood flow redistribution following minimally invasive microvessel laser ablation.Scientific reports · 2024Article
- Article
- Exercise induces superoxide and NOX4 contribution in endothelium-dependent dilation in coronary arterioles from a swine model of chronic myocardial ischemia.Microvascular research · 2023Article
- KCurrent topics in membranes · 2022Review
- Coronary microvascular adaptations distal to epicardial artery stenosis.American journal of physiology. Heart and circulatory physiology · 2021Review
- Review
- Endurance Exercise Intervention Is Beneficial to Kidney Function in a Rat Model of Isolated Abdominal Venous Congestion: a Pilot Study.Journal of cardiovascular translational research · 2020Article
- Guidelines for animal exercise and training protocols for cardiovascular studies.American journal of physiology. Heart and circulatory physiology · 2020Review
- Exercise Training as a Mediator for Enhancing Coronary Collateral Circulation: A Review of the Evidence.Current cardiology reviews · 2020Review
- The Human Coronary Collateral Circulation, Its Extracardiac Anastomoses and Their Therapeutic Promotion.International journal of molecular sciences · 2019Review
- Physical Activity in the Prevention and Treatment of Coronary Artery Disease.Journal of the American Heart Association · 2018Review
- Regulation of Coronary Blood Flow.Comprehensive Physiology · 2017Review
- [Exercise training in the therapy of heart diseases: Current evidence and future options].Herz · 2016Review
- Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion.Microvascular research · 2015Article
- Pilot study testing the effect of physical training over the myocardial perfusion and quality of life in patients with primary microvascular angina.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Physical exercise-induced protection on ischemic cardiovascular and cerebrovascular diseases.International journal of clinical and experimental medicine · 2015Review
- Physiological mechanisms of vascular response induced by shear stress and effect of exercise in systemic and placental circulation.Frontiers in pharmacology · 2014Review
- Physical activity in patients with stable coronary heart disease: an international perspective.European heart journal · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Coronary collateral vessels serve as a natural protective mechanism to provide coronary flow to ischemic myocardium secondary to critical coronary artery stenosis. The innate collateral circulation of the normal human heart is typically minimal and considerable variability occurs in extent of collateralization in coronary artery disease patients. A well-developed collateral circulation has been documented to exert protective effects upon myocardial perfusion, contractile function, infarct size, and electrocardiographic abnormalities. Thus therapeutic augmentation of collateral vessel development and/or functional adaptations in collateral and collateral-dependent arteries to reduce resistance into the ischemic myocardium represent a desirable goal in the management of coronary artery disease. Tremendous evidence has provided documentation for the therapeutic benefits of exercise training programs in patients with coronary artery disease (and collateralization); mechanisms that underlie these benefits are numerous and multifaceted, and currently under investigation in multiple laboratories worldwide. The role of enhanced collateralization as a major beneficial contributor has not been fully resolved. This topical review highlights literature that examines the effects of exercise training on collateralization in the diseased heart, as well as effects of exercise training on vascular endothelial and smooth muscle control of regional coronary tone in the collateralized heart. Future directions for research in this area involve further delineation of cellular/molecular mechanisms involved in effects of exercise training on collateralized myocardium, as well as development of novel therapies based on emerging concepts regarding exercise training and coronary artery disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.